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Product Introduction

Bioactivity

Description	Thymine is one of the four bases of DNA and is able to act as a target for 5-fluorouracil in animal cancer models with Km=2.3 μM.
Alias	5-methyluracil

Chemical Properties

Molecular Weight	126.11
Formula	C₅H₆N₂O₂
Cas No.	65-71-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (436.13 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	7.9296 mL	39.6479 mL	79.2959 mL	396.4793 mL
5 mM	1.5859 mL	7.9296 mL	15.8592 mL	79.2959 mL
10 mM	0.7930 mL	3.9648 mL	7.9296 mL	39.6479 mL
20 mM	0.3965 mL	1.9824 mL	3.9648 mL	19.8240 mL
50 mM	0.1586 mL	0.7930 mL	1.5859 mL	7.9296 mL
100 mM	0.0793 mL	0.3965 mL	0.7930 mL	3.9648 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ThymineInhibitorEndogenous Metaboliteinhibit