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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Top1 inhibitor 1 is a potent inhibitor of human topoisomerase I (Top1)(IC50: 29 nM). |
In vitro | Top1 inhibitor 1 reveals cytotoxicity in cancerous cells including MCF7 with IC50 of 2.74 μM, HeLa with IC50 of 2.61 μM, HCT116 with IC50 of 2.34 μM, NIH: OVCAR-3 (IC50: 2.35 μM) cells compared to the non-cancerous cells like HEK293 (IC50: 8.34 μM) . |
Molecular Weight | 426.47 |
Formula | C24H22N6O2 |
Cas No. | 2302772-05-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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