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Uracil

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Catalog No. T0069Cas No. 66-22-8

Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions.

Uracil

Uracil

🥰Excellent
Purity: 99.89%
Catalog No. T0069Cas No. 66-22-8
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions.
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100 mg$50In Stock
1 mL x 10 mM (in DMSO)$50In Stock
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Purity:99.89%
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Product Introduction

Bioactivity
Description
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions.
In vivo
Uracil serves both as a pharmaceutical agent and as a vehicle for drug delivery. In humans and plants, uracil functions is a conformational regulator and coenzyme in various reactions. It also plays a role in the biosynthesis of polysaccharides and the transportation of aldoses. Uracil reacts with fluorine to form 5-fluorouracil, which inhibits RNA polymerase, obstructing RNA synthesis and consequently suppressing the growth of cancer cells. Within the body, uracil binds with ribose and phosphate, aiding insynthesizing enzymes essential for numerous cellular functions.
Chemical Properties
Molecular Weight112.09
FormulaC4H4N2O2
Cas No.66-22-8
SmilesO=C1NC=CC(=O)N1
Relative Density.1.321 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 18.33 mg/mL (163.56 mM), Sonication is recommended.
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 21 mg/mL (187.3 mM)
Solution Preparation Table
DMSO/Ethanol
1mg5mg10mg50mg
1 mM8.9214 mL44.6070 mL89.2140 mL446.0701 mL
5 mM1.7843 mL8.9214 mL17.8428 mL89.2140 mL
10 mM0.8921 mL4.4607 mL8.9214 mL44.6070 mL
20 mM0.4461 mL2.2304 mL4.4607 mL22.3035 mL
50 mM0.1784 mL0.8921 mL1.7843 mL8.9214 mL
100 mM0.0892 mL0.4461 mL0.8921 mL4.4607 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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