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Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | $50 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions. |
In vivo | Uracil serves both as a pharmaceutical agent and as a vehicle for drug delivery. In humans and plants, uracil functions is a conformational regulator and coenzyme in various reactions. It also plays a role in the biosynthesis of polysaccharides and the transportation of aldoses. Uracil reacts with fluorine to form 5-fluorouracil, which inhibits RNA polymerase, obstructing RNA synthesis and consequently suppressing the growth of cancer cells. Within the body, uracil binds with ribose and phosphate, aiding insynthesizing enzymes essential for numerous cellular functions. |
Molecular Weight | 112.09 |
Formula | C4H4N2O2 |
Cas No. | 66-22-8 |
Smiles | O=C1NC=CC(=O)N1 |
Relative Density. | 1.321 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 18.33 mg/mL (163.56 mM), Sonication is recommended. H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 21 mg/mL (187.3 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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