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Vitamin E succinate

Catalog No. T64914Cas No. 4345-03-3

Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.

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Pack Size	Price	Availability
50 mg	$30	7-10 days
100 mg	$40	7-10 days
500 mg	$77	7-10 days
1 g	$113	7-10 days

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Product Introduction

Bioactivity

Description	Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol that belongs to the vitamin E class of compounds Vitamin E succinate has antitumor activity, induces apoptosis, and is used as an adjuvant in the treatment of cancer and in the synthesis of INVITE, a biocoupling compound.
In vitro	In the HEI-OC1 cell line,Vitamin E succinate (1-20 μM; 24 hours) significantly induced cytotoxicity at a concentration of 20 μM and showed a higher cytotoxic potency compared to 10 μM[1].
In vivo	In female C57BL/6 mice aged 6-8 weeks with TC-1 tumor cells,Vitamin E succinate (2 mg/kg; intraperitoneal injection; three times every 2 days, starting from the injection of TC-1 tumor cells and continuing for 10 to 14 days) decreased tumor volume[2].
Alias	D-α-Tocopherol Succinate

Chemical Properties

Molecular Weight	530.78
Formula	C33H54O5
Cas No.	4345-03-3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 120 mg/mL (226.08 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8840 mL	9.4201 mL	18.8402 mL	94.2010 mL
5 mM	0.3768 mL	1.8840 mL	3.7680 mL	18.8402 mL
10 mM	0.1884 mL	0.9420 mL	1.8840 mL	9.4201 mL
20 mM	0.0942 mL	0.4710 mL	0.9420 mL	4.7100 mL
50 mM	0.0377 mL	0.1884 mL	0.3768 mL	1.8840 mL
100 mM	0.0188 mL	0.0942 mL	0.1884 mL	0.9420 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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