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(-)-Indolactam V

Catalog No. T17299 CAS 90365-57-4

Synonyms: Indolactam V

(-)-Indolactam V is a PKC activator (Kis: 3.36 nM, 1.03 μM for η-CRD2 , γ-CRD2). (-)-Indolactam V also has the Kds are 5.5 nM (η-C1B), 7.7 nM (ε-C1B), 8.3 nM (δ-C1B), 18.9 nM (β-C1A-long), 20.8 nM (α-C1A-long), 137 nM (β-C1B), 138 nM (γ-C1A), 213 nM (γ-C1B). It has antitumor activity.

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(-)-Indolactam V, CAS 90365-57-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Targets&IC50

PKCε-C1B:7.7 nM （kd）, PKCη-C1A:3770 nM （kd）, PKCγ-C1B:213 nM （kd）, PKCβ-C1A-long:18.9 nM （kd）, PKCδ-C1B:8.3 nM （kd）, PKCθ-C1B:8.7 nM （kd）, PKCη-CRD2:3.36 nM （ki）, PKCδ-C1A:1900 nM （kd）, PKCη-C1B:5.5 nM （kd）, PKCγ-C1A:138 nM （kd）, PKCε-C1A:4110 nM （kd）, PKCγ-CRD2:1030 nM （ki）, PKCα-C1B-long:4000 nM （kd）, PKCβ-C1B:137 nM （kd）, PKCα-C1A-long:20.8 nM （kd）

Synonyms	Indolactam V
Molecular Weight	301.39
Formula	C17H23N3O2
CAS No.	90365-57-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

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( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

(-)-Indolactam V 90365-57-4 Chromatin/Epigenetic Cytoskeletal Signaling PKC ()Indolactam V ( ) Indolactam V Indolactam V Inhibitor inhibitor inhibit

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