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(S)-Indoximod
🥰Excellent
Catalog No. T3S1967Cas No. 21339-55-9
Alias N-ME-Tryptophan, L-Abrine, 1-Methyl-L-tryptophan
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.
(S)-Indoximod
🥰Excellent
Purity: 95.39%
Catalog No. T3S1967Alias N-ME-Tryptophan, L-Abrine, 1-Methyl-L-tryptophanCas No. 21339-55-9
(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 mg | $29 | In Stock |
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Purity:95.39%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | (S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM. |
| Targets&IC50 | IDO:3-Dioxygenase |
| Alias | N-ME-Tryptophan, L-Abrine, 1-Methyl-L-tryptophan |
| Molecular Weight | 218.25 |
| Formula | C12H14N2O2 |
| Cas No. | 21339-55-9 |
| Smiles | Cn1cc(C[C@H](N)C(O)=O)c2ccccc12 |
| Relative Density. | 1.28g/cm3 |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | 0.1 M NaOH: 10 mg/mL (45.8 mM), Sonication is recommended.  DMSO: Slightly soluble | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
0.1 M NaOH
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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