Shopping Cart
- Remove All
Your shopping cart is currently empty
IDO-IN-7
🥰Excellent
Catalog No. T1806Cas No. 1402836-58-1
Alias NLG-919 analogue, NLG919, Navoximod, GDC-0919
IDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway.
IDO-IN-7
🥰Excellent
Purity: 100%
Catalog No. T1806Alias NLG-919 analogue, NLG919, Navoximod, GDC-0919Cas No. 1402836-58-1
IDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $38 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $95 | In Stock | |
| 25 mg | $153 | In Stock | |
| 50 mg | $252 | In Stock | |
| 100 mg | $450 | In Stock | |
| 500 mg | $987 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $58 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "IDO-IN-7"
Indoximod
Cited
NLG-8189, Indoximod (NLG-8189）, 1-Methyl-D-tryptophan
T6543110117-83-4
Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
- $40
Size
QTY
CitedEpacadostat
Cited
INCB 024360, IDO Inhibitor 1
T35481204669-58-8
Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.
- $39
Size
QTY
CitedPalmatine Cited
Burasaine, Berbericinine
T5S08023486-67-7
1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases.
- $55
Size
QTY
CitedPalmatine chloride
T271810605-02-4
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
- $39
Size
QTY
GNF-PF-3777
8-Nitrotryptanthrin
T1019977603-42-0
GNF-PF-3777 (8-Nitrotryptanthrin) is a potent inhibitor of human indoleamine 2,3-dioxygenase 2 (hIDO2) with a Ki of 0.97 μM.
- $30
Size
QTY
Necrostatin-1 Cited
Necrostatin 1, Nec-1
T18474311-88-0
Necrostatin-1 (Nec-1) is a specific RIP1 inhibitor and necrotic apoptosis inhibitor, which inhibits TNF-α-induced necrotic apoptosis and also inhibits IDO.
- $30
Size
QTY
CitedCoptisine chloride
Q-100696, NSC-119754
T5S00566020-18-4
1. Coptisine chloride (NSC-119754) can be absorbed across intestinal epithelial cells, and completely absorbed compounds.
- $59
Size
QTY
IDO-IN-12
T116151888341-29-4In house
IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).
- $81
Size
QTY
IDO5L
INCB14943, INCB024360 analogue
T2647914471-09-3
IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).
- $43
Size
QTY
IDO inhibitor 1
T76601204669-37-3
IDO inhibitor 1 is an potent inhibitor of indoleamine-2,3 dioxygenase (IDO) ( IC50 <100 nM).with potential immunomodulating and antineoplastic activities.
- $91
Size
QTY
Coptisine sulfate
T4S00511198398-71-8
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
- $47
Size
QTY
IDO-IN-1
T7181914638-30-5
IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with IC50 values of 59 nM for human IDO enzymatic activity and 12 nM for HeLa cell assays.
- $47
Size
QTY
Select Batch
Purity:100%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | IDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway. |
| Targets&IC50 | IDO:75 nM(EC50) |
| In vitro | In mice bearing B16F10 tumors, NLG919 significantly enhanced the antitumor response of pmel-1 resting cells to homologous hgp100 peptide and CpG-1826. |
| In vivo | NLG919 effectively blocks the IDO-induced suppression of T-cell responses, restoring T-cell activity (ED50=80 nM). In mouse dendritic cells (DCs) expressing IDO from tumor lymph nodes (ED50=120 nM), NLG919 abolishes the IDO-induced inhibition of antigen-specific T-cells (OT-1). |
| Alias | NLG-919 analogue, NLG919, Navoximod, GDC-0919 |
| Molecular Weight | 282.38 |
| Formula | C18H22N2O |
| Cas No. | 1402836-58-1 |
| Smiles | OC(CC1c2ccccc2-c2cncn12)C1CCCCC1 |
| Relative Density. | 1.27 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | Ethanol: 26 mg/mL (92.1 mM) DMSO: 45 mg/mL (159.36 mM)  H2O: < 1 mg/mL (insoluble or slightly soluble) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
| |||||||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy IDO-IN-7 | purchase IDO-IN-7 | IDO-IN-7 cost | order IDO-IN-7 | IDO-IN-7 chemical structure | IDO-IN-7 in vivo | IDO-IN-7 in vitro | IDO-IN-7 formula | IDO-IN-7 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.