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(+)-Fluprostenol

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Purity:99.56%

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COA HNMR HPLC

(+)-Fluprostenol

Catalog No. T21224Cas No. 54276-17-4

(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).

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Pack Size	Price	Availability
1 mg	$77	In Stock
5 mg	$189	In Stock
10 mg	$313	In Stock
25 mg	$578	In Stock
50 mg	$833	In Stock
100 mg	$1,150	In Stock
1 mL x 10 mM (in DMSO)	$223	In Stock

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Product Introduction

Bioactivity

Description	(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).
In vivo	(+)-Fluprostenol(s.c. to rats on day 18 of pregnancy) increased cervical creep, or softness, by the following day. Doses of (+)-Fluprostenol 100-fold larger were necessary to increase uterine contractions. (+)-Fluprostenol produced falls in serum progesterone concentrations, increases in 20 alpha-dihydroprogesterone concentrations, no changes in oestradiol or relaxin concentrations and a reduction in the ovarian human chorionic gonadotrophin binding capacity in vitro. (+)-Fluprostenol was less potent in inducing cervical softness when administered per vaginam, and a dose which produced softening in pregnant rats was ineffective in ovariectomized steroid-maintained pregnant or pro-oestrous rats[3].
Alias	Fluprostenol, (+)-, Travoprost acid, AL-5848

Chemical Properties

Molecular Weight	458.47
Formula	C23H29F3O6
Cas No.	54276-17-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 325 mg/mL (708.88 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1812 mL	10.9058 mL	21.8117 mL	109.0584 mL
5 mM	0.4362 mL	2.1812 mL	4.3623 mL	21.8117 mL
10 mM	0.2181 mL	1.0906 mL	2.1812 mL	10.9058 mL
20 mM	0.1091 mL	0.5453 mL	1.0906 mL	5.4529 mL
50 mM	0.0436 mL	0.2181 mL	0.4362 mL	2.1812 mL
100 mM	0.0218 mL	0.1091 mL	0.2181 mL	1.0906 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

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