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(E/Z)-E64FC26
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Catalog No. T39812Cas No. 2285446-67-3
(E/Z)-E64FC26 is a potent protein disulfide isomerase (PDI) family inhibitor with potential antitumor activity and affinity for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6. (E/Z)-E64FC26 can be used for myeloma research.
(E/Z)-E64FC26
😃Good
Purity: 98.23%
Catalog No. T39812Cas No. 2285446-67-3
(E/Z)-E64FC26 is a potent protein disulfide isomerase (PDI) family inhibitor with potential antitumor activity and affinity for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6. (E/Z)-E64FC26 can be used for myeloma research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $332 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $333 | 7-10 days |
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Purity:98.23%
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Product Introduction
Bioactivity
Chemical Properties
| Description | (E/Z)-E64FC26 is a potent protein disulfide isomerase (PDI) family inhibitor with potential antitumor activity and affinity for PDIA1, PDIA3, PDIA4, TXNDC5 and PDIA6. (E/Z)-E64FC26 can be used for myeloma research. |
| Targets&IC50 | TXNDC5:16.3 μM, PDIA6:25.4 μM, PDIA4:25.9 μM, PDIA1:1.9 μM, PDIA3:20.9 μM |
| In vitro | (E/Z)-E64FC26 is an effective broad-spectrum inhibitor of the protein disulfide isomerase (PDI) family, with half-maximal inhibitory concentrations (IC50) of 1.9, 20.9, 25.9, 16.3, and 25.4 μM for PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6, respectively. Additionally, (E/Z)-E64FC26 demonstrates anti-myeloma activity. [1][2] |
| Molecular Weight | 340.38 |
| Formula | C19H23F3O2 |
| Cas No. | 2285446-67-3 |
| Smiles | FC(F)(F)C1=CC(=CCCCCCCCC)C=2C=C(O)C(O)=CC21 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80.00 mg/mL (235.03 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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