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1,7-Diphenyl-4-hepten-3-one
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Catalog No. TN2522Cas No. 79559-59-4
1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.
1,7-Diphenyl-4-hepten-3-one
😃Good
Catalog No. TN2522Cas No. 79559-59-4
1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $1,487 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $1,798 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1,7-Diphenyl-4-hepten-3-one is a compound isolated from Alpinia officinarum, which activates the Nrf2 pathway to suppress pyroptosis. It alleviates cognitive impairment and pathological damage in APP/PS1 mice and prevents oxidative stress damage while reducing levels of pyroptosis-related proteins. 1,7-Diphenyl-4-hepten-3-one enhances Aβ-induced proliferation in HT22 cells and can be used in Alzheimer’s disease research. |
| In vitro | 1,7-Diphenyl-4-hepten-3-one prevents oxidative stress damage and reduces the levels of pyrogenic proteins. 1,7-Diphenyl-4-hepten-3-one improves Aβ-induced proliferation of HT22 cells and reduces the level of pyroxy-associated proteins. [1] |
| In vivo | 1,7-Diphenyl-4-hepten-3-one can alleviate AD-like pathology by activating Nrf2 pathway to inhibit pyrodeath. [1] |
| Molecular Weight | 264.36 |
| Formula | C19H20O |
| Cas No. | 79559-59-4 |
| Smiles | O=C(C=CCCC=1C=CC=CC1)CCC=2C=CC=CC2 |
| Relative Density. | 1.031 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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