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1-Deoxymannojirimycin hydrochloride, a selective α1,2-mannosidase inhibitor (IC50: 20 μM), also inhibits HIV-1 strains but exhibits poor antiviral activity.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $68 | 35 days | |
5 mg | $210 | 35 days | |
10 mg | $315 | 35 days | |
25 mg | $525 | 35 days |
Description | 1-Deoxymannojirimycin hydrochloride, a selective α1,2-mannosidase inhibitor (IC50: 20 μM), also inhibits HIV-1 strains but exhibits poor antiviral activity. |
Targets&IC50 | α1/2 mannosidase I:20 μM |
In vitro | Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures[1].When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed[1]. |
Molecular Weight | 199.63 |
Formula | C6H14ClNO4 |
Cas No. | 73465-43-7 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 20 mg/mL (100.19 mM) H2O: 20 mg/mL (100.19 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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