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1-Deoxymannojirimycin hydrochloride
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Catalog No. T22468Cas No. 73465-43-7
1-Deoxymannojirimycin hydrochloride, a selective α1,2-mannosidase inhibitor (IC50: 20 μM), also inhibits HIV-1 strains but exhibits poor antiviral activity.
1-Deoxymannojirimycin hydrochloride
😃Good
Catalog No. T22468Cas No. 73465-43-7
1-Deoxymannojirimycin hydrochloride, a selective α1,2-mannosidase inhibitor (IC50: 20 μM), also inhibits HIV-1 strains but exhibits poor antiviral activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $68 | 35 days | |
| 5 mg | $210 | 35 days | |
| 10 mg | $315 | 35 days | |
| 25 mg | $525 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1-Deoxymannojirimycin hydrochloride, a selective α1,2-mannosidase inhibitor (IC50: 20 μM), also inhibits HIV-1 strains but exhibits poor antiviral activity. |
| Targets&IC50 | α1/2 mannosidase I:20 μM |
| In vitro | Exposure of such mutant virus strains to 1-Deoxymannojirimycin results in an enhanced suppression of mutant virus-induced cytopathicity in CEM cell cultures[1].When combined with CBAs at concentrations that showed poor if any suppression of mutant virus replication as single drugs, a synergistic antiviral activity of 1-Deoxymannojirimycin was observed[1]. |
| Molecular Weight | 199.63 |
| Formula | C6H14ClNO4 |
| Cas No. | 73465-43-7 |
| Smiles | Cl.OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 20 mg/mL (100.19 mM) H2O: 20 mg/mL (100.19 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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