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2,2-Dihydroxyacetic acid

2,2-Dihydroxyacetic acid
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2,2-Dihydroxyacetic acid

Catalog No. T4843Cas No. 563-96-2
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated with primary hyperoxaluria, an inborn error of metabolism. As an aldehyde, glyoxalate is also highly active and can modify proteins to form advanced glycosylation products (AGEs).
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Pack SizePriceAvailabilityQuantity
1 g$29In Stock
5 g$47In Stock
10 g$68In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Product Introduction

Bioactivity
Description
2,2-Dihydroxyacetic acid (Formylformic acid) is an intermediate in the glyoxalate cycle, which enables certain organisms to convert fatty acids to carbohydrates.2,2-Dihydroxyacetic acid has been found to be associated with primary hyperoxaluria, an inborn error of metabolism. As an aldehyde, glyoxalate is also highly active and can modify proteins to form advanced glycosylation products (AGEs).
AliasFormylformic acid, Glyoxylic acid monohydrate
Chemical Properties
Molecular Weight92.05
FormulaC2H4O4
Cas No.563-96-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 25 mg/mL (271.59 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM10.8637 mL54.3183 mL108.6366 mL543.1831 mL
5 mM2.1727 mL10.8637 mL21.7273 mL108.6366 mL
10 mM1.0864 mL5.4318 mL10.8637 mL54.3183 mL
20 mM0.5432 mL2.7159 mL5.4318 mL27.1592 mL
50 mM0.2173 mL1.0864 mL2.1727 mL10.8637 mL
100 mM0.1086 mL0.5432 mL1.0864 mL5.4318 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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