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2-TEDC

Catalog No. T22502Cas No. 132465-10-2

2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.2-TEDC can be used in the study of atherosclerosis.

2-TEDC

2-TEDC

Purity: 99.75%
Catalog No. T22502Cas No. 132465-10-2
2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.2-TEDC can be used in the study of atherosclerosis.
Pack SizePriceAvailabilityQuantity
10 mg$31In Stock
25 mg$64In Stock
50 mg$98In Stock
100 mg$163In Stock
1 mL x 10 mM (in DMSO)$35In Stock
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Purity:99.75%
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Product Introduction

Bioactivity
Description
2-TEDC is a potent lipoxygenase (LOX) inhibitor with inhibitory effects on 5-LOX, 12-LOX, and 15-LOX with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.2-TEDC can be used in the study of atherosclerosis.
Targets&IC50
5-LOX:0.09 μM, 12-LOX:0.013 μM, 15-LOX:0.5 μM
In vitro
2-TEDC exhibits potent inhibition against 5-, 12-, and 15-lipoxygenase, with IC50 values of 0.09 μM, 0.013 μM, and 0.5 μM, respectively.[1]
Chemical Properties
Molecular Weight315.34
FormulaC16H13NO4S
Cas No.132465-10-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 90.0 mg/mL (285.4 mM), Sonication is recommended.
Ethanol: 25 mM
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM3.1712 mL15.8559 mL31.7118 mL158.5590 mL
5 mM0.6342 mL3.1712 mL6.3424 mL31.7118 mL
10 mM0.3171 mL1.5856 mL3.1712 mL15.8559 mL
20 mM0.1586 mL0.7928 mL1.5856 mL7.9280 mL
DMSO
1mg5mg10mg50mg
50 mM0.0634 mL0.3171 mL0.6342 mL3.1712 mL
100 mM0.0317 mL0.1586 mL0.3171 mL1.5856 mL

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