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5-Amino-3H-imidazole-4-Carboxamide

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Catalog No. T1705Cas No. 360-97-4
Alias AICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamide

5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.

5-Amino-3H-imidazole-4-Carboxamide

5-Amino-3H-imidazole-4-Carboxamide

🥰Excellent
Purity: 99.9%
Catalog No. T1705Alias AICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamideCas No. 360-97-4
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
Pack SizePriceAvailabilityQuantity
1 g$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.9%
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Product Introduction

Bioactivity
Description
5-Amino-3H-imidazole-4-Carboxamide (AICA) is an imidazole derivative and a metabolite of the antineoplastic agents BIC and DIC. It serves as a condensation agent in the preparation of nucleosides and nucleotides, and when compounded with orotic acid, it is used to treat liver diseases.
AliasAICA, 5-Aminoimidazole-4-carboxamide, 4-Amino-5-imidazolecarboxamide
Chemical Properties
Molecular Weight126.12
FormulaC4H6N4O
Cas No.360-97-4
SmilesNC(=O)C1=C(N)NC=N1
Relative Density.1.3659 g/cm3 (Estimated)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (792.90 mM), Sonication is recommended.
H2O: 20 mg/mL (158.58 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM7.9290 mL39.6448 mL79.2896 mL396.4478 mL
5 mM1.5858 mL7.9290 mL15.8579 mL79.2896 mL
10 mM0.7929 mL3.9645 mL7.9290 mL39.6448 mL
20 mM0.3964 mL1.9822 mL3.9645 mL19.8224 mL
50 mM0.1586 mL0.7929 mL1.5858 mL7.9290 mL
100 mM0.0793 mL0.3964 mL0.7929 mL3.9645 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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