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5-Hydroxy-7,8-dimethoxyflavanone
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Catalog No. TN3119Cas No. 113981-49-0
5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.
5-Hydroxy-7,8-dimethoxyflavanone
😃Good
Catalog No. TN3119Cas No. 113981-49-0
5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $2,590 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity. |
| In vitro | 5-Hydroxy-7,8-dimethoxyflavanone efficiently increased the susceptibility of CYP6AA3- and CYP6P7-expressing Spodoptera frugiperda (Sf9) cells to cypermethrin toxicity, due to inhibition effects on mosquito enzymes[1]. 5-Hydroxy-7,8-dimethoxyflavanone significantly decreases TNF-alpha, IL-6, macrophage inflammatory protein-2 (MIP-2), and nitric oxide (NO) secretions from LPS/IFN-gamma stimulated RAW 264.7 cells[2]. |
| Molecular Weight | 300.31 |
| Formula | C17H16O5 |
| Cas No. | 113981-49-0 |
| Smiles | O=C1C2=C(O)C=C(OC)C(OC)=C2OC(C=3C=CC=CC3)C1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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