Shopping Cart
- Remove All
Your shopping cart is currently empty
AX20017
🥰Excellent
Catalog No. T7312Cas No. 329221-38-7
AX20017, a small-molecule protein kinase G (PknG) inhibitor (IC50: 0.39 μM), functions by inhibiting the proliferation of M. tuberculosis.
AX20017
🥰Excellent
Purity: 99.31%
Catalog No. T7312Cas No. 329221-38-7
AX20017, a small-molecule protein kinase G (PknG) inhibitor (IC50: 0.39 μM), functions by inhibiting the proliferation of M. tuberculosis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $43 | In Stock | |
| 5 mg | $65 | In Stock | |
| 10 mg | $92 | In Stock | |
| 25 mg | $198 | In Stock | |
| 50 mg | $343 | In Stock | |
| 100 mg | $516 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $75 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "AX20017"
Dimethyl sulfoxide
Cited
Methyl Sulfoxide, DMSO
T034167-68-5
Dimethyl sulfoxide (DMSO) is a commonly used solvent to dissolve polar and non-polar compounds. Dimethyl sulfoxide has been widely used for masterbatch preparation of compounds in biological experiments. Dimethyl sulfoxide has bacteriostatic activity.
- $45
Size
QTY
CitedNeomycin sulfate Cited
Framycin sulfate
T09501405-10-3
Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.
- $43
Size
QTY
CitedSulfamethoxazole sodium
Ro 4-2130 sodium
T81394563-84-2
Sulfamethoxazole sodium (Ro 4-2130 sodium) is a sulfonamide bacteriostatic antibiotic.
- $32
Size
QTY
Doxycycline Cited
Vibramycin, Doxytetracycline, Doxycyclinum, Doxiciclina
T1687564-25-0
Doxycycline (Doxiciclina) belongs to the tetracycline class of antibiotics and is a broad-spectrum metalloproteinase (MMP) inhibitor with oral activity. Doxycycline has antibacterial activity and antitumor activity.
- $45
Size
QTY
CitedKanamycin sulfate
Ophtalmokalixan, Kanamycin monosulfate, Kanamycin A monosulfate
T079325389-94-0
Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.
- $41
Size
QTY
Ampicillin sodium Cited
Penialmen, Domicillin, D-(-)-α-Aminobenzylpenicillin sodium salt, Citteral
T638669-52-3
Ampicillin Sodium is the sodium salt form of ampicillin, a broad-spectrum semisynthetic derivative of aminopenicillin. Ampicillin sodium (Domicillin) inhibits bacterial cell wall synthesis by binding to penicillin binding proteins, thereby inhibiting peptidoglycan synthesis, a critical component of the bacterial cell wall.
- $50
Size
QTY
CitedDehydroacetic acid sodium
Sodium dehydroacetate
T224274418-26-2
Dehydroacetic acid sodium (Sodium dehydroacetate) is the sodium salt of dehydroacetic acid, a bactericide and fungicide that is commonly used as a food preservative. Dehydroacetic acid sodium is a preservative that is used in the formulation of personal care products and cosmetics in order to extend the shelf-life by preventing microbial contamination.
- $31
Size
QTY
Methyl anthranilate
TN1925134-20-3
Methyl anthranilate is a natural product. Methyl anthranilate is a novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria
- $50
Size
QTY
Metronidazole Cited
Metronidazol, Flagyl, Anagiardil
T1079443-48-1
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
- $30
Size
QTY
CitedCrystal Violet Cited
Methyl Violet 10B, Hexamethylpararosaniline chloride, Gentian Violet, Basic Violet 3
T1343L548-62-9
Crystal Violet (Hexamethylpararosaniline chloride) is a triarylmethane dye that is a mixture of violet rosanilinis, with antibacterial, antifungal, and anthelmintic properties.
- $46
Size
QTY
CitedG-418 disulfate Cited
Geneticin sulfate, Geneticin, G418 Sulfate, Antibiotic G-418 sulfate
T6512108321-42-2
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.
- $42
Size
QTY
CitedRifampicin Cited
Rimactane, Rifamycin AMP, Rifampin
T068113292-46-1
Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses.
- $45
Size
QTY
CitedSelect Batch
Purity:99.31%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | AX20017, a small-molecule protein kinase G (PknG) inhibitor (IC50: 0.39 μM), functions by inhibiting the proliferation of M. tuberculosis. |
| Targets&IC50 | PKNG:0.39 μM |
| In vitro | The inhibitory activity of AX20017 against the 11 known mycobacterial kinases revealed that the compound is highly selective for PknG . To test the activity of the inhibitor toward eukaryotic kinases, a screen of 28 different archetypical human kinases originating from six major protein kinase groups was set up. AX20017 did not affect the human kinases, whereas the activity of PknG was effectively inhibited[1]. |
| Molecular Weight | 264.34 |
| Formula | C13H16N2O2S |
| Cas No. | 329221-38-7 |
| Smiles | NC(=O)c1c(NC(=O)C2CC2)sc2CCCCc12 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 32 mg/mL (121.06 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy AX20017 | purchase AX20017 | AX20017 cost | order AX20017 | AX20017 chemical structure | AX20017 in vitro | AX20017 formula | AX20017 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.