Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 38.00 | |
2 mg | In stock | $ 54.00 | |
5 mg | In stock | $ 89.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 226.00 | |
50 mg | In stock | $ 397.00 | |
100 mg | In stock | $ 597.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 97.00 |
Description | Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator. |
In vivo | After oral administration of amiselimod or fingolimod at 1 mg/kg, the concentration of amiselimod-P in rat heart tissue was relatively lower than that of fingolimod-P, potentially contributing to the minimal cardiac effects of amiselimod. Amiselimod-P showed potent selectivity for S1P1, high selectivity for S1P5, minimal agonist activity for S1P4, no distinct agonist activity for S1P2 or S1P3, and approximately 5-fold weaker GIRK activation than fingolimod-P [1]. Amiselimod 0·2 mg and 0·4 mg significantly reduced the total number of gadolinium-enhanced T1-weighted lesions [2]. |
Synonyms | MT-1303 hydrochloride |
Molecular Weight | 413.9 |
Formula | C19H31ClF3NO3 |
CAS No. | 942398-84-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27mg/ml (65.23 mM)
You can also refer to dose conversion for different animals. More
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Amiselimod hydrochloride 942398-84-7 GPCR/G Protein S1P Receptor LPL Receptor Amiselimod inhibit MT-1303 Hydrochloride MT-1303 hydrochloride MT 1303 MT-1303 MT1303 MT1303 Hydrochloride Inhibitor MT 1303 Hydrochloride Amiselimod Hydrochloride Lysophospholipid Receptor inhibitor