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Antalarmin hydrochloride

Catalog No. T22577   CAS 220953-69-5

Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.

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Antalarmin hydrochloride Chemical Structure
Antalarmin hydrochloride, CAS 220953-69-5
Pack Size Availability Price/USD Quantity
1 mg In stock $ 41.00
5 mg In stock $ 97.00
10 mg In stock $ 155.00
25 mg In stock $ 313.00
50 mg In stock $ 466.00
100 mg In stock $ 683.00
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Purity: 100%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Antalarmin hydrochloride is an antagonist of corticotropin-releasing factor 1(CRF1). Antalarmin hydrochloride produces anti-inflammatory effects and suppresses stress-induced gastric ulceration related to irritable bowel syndrome.
Molecular Weight 415.02
Formula C24H35ClN4
CAS No. 220953-69-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 11.7mg/mL (28.2mM), sonification is recommended.

TargetMolReferences and Literature

1. Zorrilla EP, et al. Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat. Brain Res. 2002 Oct 18;952(2):188-99. 2. Deak T, et al. The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress. Endocrinology. 1999 Jan;140(1):79-86. 3. Webster EL, et al. In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation. Endocrinology. 1996 Dec;137(12):5747-50.

Related compound libraries

This product is contained In the following compound libraries:
Bioactive Compounds Library Max Inhibitor Library Bioactive Compound Library

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Keywords

Antalarmin hydrochloride 220953-69-5 GPCR/G Protein Immunology/Inflammation CRFR Immunology/Inflammation related Antalarmin Hydrochloride inhibitor inhibit

 

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