Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 98.00 | |
5 mg | In stock | $ 263.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 629.00 | |
50 mg | In stock | $ 896.00 | |
100 mg | In stock | $ 1,220.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 288.00 |
Description | BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator. |
In vitro | BMS-191095 elicits a dose-dependent vasodilation in endothelium-denuded cerebral arteries with 8.1 ± 2.3%, 31.6 ± 2.1%, and 39.5 ± 3.2% relaxation in response to 10, 50, and 100 μM, respectively. BMS-191095 induces mitochondrial-depolarization and vasodilation. |
In vivo | In normal rats, BMS-191095-induced vasodilation was mediated by mitochondrial depolarization and calcium sparks generation in VSM and was reduced by inhibition of BKCa channels. |
Molecular Weight | 408.88 |
Formula | C22H21ClN4O2 |
CAS No. | 166095-21-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (220.11 mM)
You can also refer to dose conversion for different animals. More
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BMS-191095 166095-21-2 Membrane transporter/Ion channel Potassium Channel Inhibitor BMS191095 KcsA BMS 191095 inhibit inhibitor