Shopping Cart
- Remove All
- Your shopping cart is currently empty
Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong inhibitory effect on type A monoamine oxidase and weak inhibitory effect on type b monoamine oxidase. Bazinaprine is reversible in vivo, but not in vitro.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $92 | In Stock | |
5 mg | $231 | In Stock | |
10 mg | $328 | In Stock | |
25 mg | $493 | In Stock | |
50 mg | $666 | In Stock | |
100 mg | $900 | In Stock | |
200 mg | $1,180 | In Stock | |
1 mL x 10 mM (in DMSO) | $215 | In Stock |
Description | Bazinaprine is a selective, reversible monoamine oxidase inhibitor (MAOI) that is a candidate compound for the treatment of depression. Bazinaprine showed strong inhibitory effect on type A monoamine oxidase and weak inhibitory effect on type b monoamine oxidase. Bazinaprine is reversible in vivo, but not in vitro. |
Targets&IC50 | MAO-A:3-5mg/kg(ED50) |
In vitro | Bazinaprine(SR 95191) inhibits MAO-A in a time-dependent manner in vitro and appears to be irreversible.[1] The inhibition of brain MAO-A, but not MAO-B, by SR 95191 was time dependent, with a 19-fold decrease in the IC50 values being observed over a 30-min incubation period (140 to 7.5 μM).[2] |
In vivo | Bazinaprine (1–100 mg/kg, p.o.) antagonized, in a dose-dependent fashion, the irreversible inhibition of brain and liver MAO-A induced by phenelzine.[2] |
Molecular Weight | 309.37 |
Formula | C17H19N5O |
Cas No. | 94011-82-2 |
Smiles | C(#N)C=1C=C(N=NC1NCCN2CCOCC2)C3=CC=CC=C3 |
Storage | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 22.5 mg/mL (72.73 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.