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Bromelain

Catalog No. T10619 CAS 9001-00-7

Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression, and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway.

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Bromelain, CAS 9001-00-7

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100 mg	In stock	$ 41.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression, and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway.
In vivo	Bromelain (40 mg/kg; i.p.; daily; for 7 days; male SD rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of Parkinson's disease. 6-OHDA injection resulted in a marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion [1].

Molecular Weight	1026.942
Formula	C39H66N2O29
CAS No.	9001-00-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 3.33 mg/mL (3.25 mM), Sonification is recommended

References and Literature

1. Adu TS, et al. Effects of bromelain on motor responses following intra-medial forebrain bundle 6-OHDA injection in rat model of parkinsonism. Metab Brain Dis. 2019 Jul 22. 2. Pavan R, et al. Properties and therapeutic application of bromelain: a review. Biotechnol Res Int. 2012;2012:976203.

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Keywords

Bromelain 9001-00-7 Apoptosis Others Inhibitor inhibit inhibitor

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