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Burixafor hydrobromide

Burixafor hydrobromide
Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent CXCR4 antagonist with anti-angiogenic properties, potentially valuable in treating choroid neovascularization.
Catalog No. T10635Cas No. 1191450-19-7

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Burixafor hydrobromide

Catalog No. T10635Alias TG-0054 hydrobromideCas No. 1191450-19-7

Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent CXCR4 antagonist with anti-angiogenic properties, potentially valuable in treating choroid neovascularization.
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
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25 mgInquiry6-8 weeks
50 mgInquiry6-8 weeks
100 mgInquiry6-8 weeks
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Product Introduction

Bioactivity
Description
Burixafor hydrobromide (TG-0054 hydrobromide) is an orally bioavailable and potent CXCR4 antagonist with anti-angiogenic properties, potentially valuable in treating choroid neovascularization.
In vitro
Burixafor hydrobromide mobilizes mesenchymal stem cells, attenuates inflammation, and preserves cardiac systolic function in a porcine model of myocardial infarction [2].
AliasTG-0054 hydrobromide
Chemical Properties
Molecular Weight647.644
FormulaC27H52BrN8O3P
Cas No.1191450-19-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 50 mg/mL (65.02 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.5441 mL7.7203 mL15.4406 mL77.2029 mL
5 mM0.3088 mL1.5441 mL3.0881 mL15.4406 mL
10 mM0.1544 mL0.7720 mL1.5441 mL7.7203 mL
20 mM0.0772 mL0.3860 mL0.7720 mL3.8601 mL
50 mM0.0309 mL0.1544 mL0.3088 mL1.5441 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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