Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 51.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 372.00 | |
50 mg | In stock | $ 556.00 | |
100 mg | In stock | $ 783.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 153.00 |
Description | CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively. |
Targets&IC50 | TrkA:1.1 nM , TrkB:7.8 nM , TrkC:5.1 nM |
In vitro | CH7057288, a potent and selective TRK inhibitor belonging to a novel chemical class.CH7057288 induced regression of intracranial tumors and greatly improved event-free survival in an intracranial implantation model mimicking brain metastasis. |
Molecular Weight | 569.67 |
Formula | C32H31N3O5S |
CAS No. | 2095616-82-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 34 mg/mL (59.68 mM)
You can also refer to dose conversion for different animals. More
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CH7057288 2095616-82-1 Tyrosine Kinase/Adaptors Trk receptor CH-7057288 Inhibitor Trk Receptor inhibit CH 7057288 Tropomyosin related kinase receptor inhibitor