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CP-640186

Catalog No. T1889 CAS 591778-68-6

Synonyms: CP 640186

CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

CP-640186, CAS 591778-68-6

Pack Size	Availability	Price/USD
1 mg	In stock	$ 41.00
5 mg	In stock	$ 97.00
10 mg	In stock	$ 157.00
25 mg	In stock	$ 257.00
50 mg	In stock	$ 353.00
100 mg	In stock	$ 526.00
1 mL * 10 mM (in DMSO)	In stock	$ 118.00

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Purity: 98.67%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.
Targets&IC50	ACC1:53 nM, ACC12:61 nM

Synonyms	CP 640186
Molecular Weight	485.62
Formula	C30H35N3O3
CAS No.	591778-68-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 45 mg/mL (92.66 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Harwood HJ Jr, et al. J Biol Chem. 2003 Sep 26;278(39):37099-111.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compound Library Lipid Metabolism Compound Library Bioactive Compounds Library Max Anti-Hypertension Compound Library Metabolism Compound Library Inhibitor Library Target-Focused Phenotypic Screening Library Anti-Cardiovascular Disease Compound Library NO PAINS Compound Library Anti-Obesity Compound Library

Related Products

Related compounds with same targets

PF-05175157 TOFA ND-646 CMS-121 PF-05221304 CP-640186 hydrochloride Tralkoxydim Firsocostat

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CP-640186 591778-68-6 Metabolism Acetyl-CoA Carboxylase H460 HepG2 human fibroblasts Inhibitor inhibit muscle fatty acid oxidation ACC, Acetyl Coenzyme A Carboxylase CP640186 C2C12 muscle strips CP 640186 inhibitor

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