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CT-2584
🥰Excellent
Catalog No. T27094Cas No. 166981-13-1
Alias CT2584, CT 2584
CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
CT-2584
🥰Excellent
Purity: 99.23%
Catalog No. T27094Alias CT2584, CT 2584Cas No. 166981-13-1
CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $333 | In Stock | |
| 5 mg | $790 | In Stock | |
| 10 mg | $1,120 | In Stock | |
| 25 mg | $1,670 | In Stock | |
| 50 mg | $2,180 | In Stock | |
| 100 mg | $2,800 | In Stock |
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Purity:99.23%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | CT-2584 is an anticancer agent that inhibits phospholipid signaling and kills tumor cells through the production of reactive oxygen intermediates. CT-2584 reduces NKEF-B expression in several tumor cell types. CT-2584 reduced tumor growth in SCID mice by causing shunting of ab initio phospholipid biosynthesis from phosphatidylcholine (PC) to phosphatidylinositol (PI) via PA. |
| In vitro | CT-2584 (0-7 μM, 3 days) was toxic to ECV304, to which B/1 cells were highly resistant. [5]；Toxicity was observed in human hepatocellular carcinoma Alex 0 cells at 3.5 mmol/L CT-2584 and Alex 0.5 cells at 2.0 mmol/L CT-2584. 24 hours later, cytotoxicity and decreased HBsAg (hepatitis B surface antigen) secretion were observed, even at lower concentrations. [6] |
| In vivo | Daily intraperitoneal injection of 25 mg/kg CT-2584 for three consecutive days was tolerated in SCID mice. When higher doses (50 mg/kg) were attempted, the animals died due to drug-related peritonitis. [6] |
| Alias | CT2584, CT 2584 |
| Molecular Weight | 533.79 |
| Formula | C30H55N5O3 |
| Cas No. | 166981-13-1 |
| Smiles | O=C1C2=C(N=CN2C)N(C(=O)N1CCCCCCCCCC(O)CNCCCCCCCCCCCC)C |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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