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Cercosporin

Cercosporin
Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).
Catalog No. T13605Cas No. 35082-49-6
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Cercosporin

Catalog No. T13605Cas No. 35082-49-6
Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).
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Product Introduction

Bioactivity
Description
Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).
Targets&IC50
PKC:0.6-1.3 μM
In vitro
Cercosporin (0-3 μΜ; 24 hours) interplays with copper results in synergistic cytotoxicity in MCF7 and T98G cells, that is, S(CuSO4 + Cerco) ? S(CuSO4) x S(Cerco), barely has an additive effect in U87 cells. Cercosporin (0.8-8.0 μM; 30 s, 60 s, 90 s, 120 s) photodynamic therapy effect is stronger in T98G cells than in U87 or MCF7 cells, the LD50 value for the T98G cells (0.14 J cm2) is much less than the LD50 value for MCF-7 and U87 cell lines (0.26 and 0.24 J cm2, respectively) [1].
Chemical Properties
Molecular Weight534.51
FormulaC29H26O10
Cas No.35082-49-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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