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Cimiside E

Catalog No. TN3655 CAS 154822-57-8

Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agent against cancer, it arrests cell cycle and induces cell apoptosis in gastric cancer cells.

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Cimiside E, CAS 154822-57-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	602.809
Formula	C35H54O8
CAS No.	154822-57-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Cimiside E 154822-57-8 DNA损伤和修复 MAPK信号通路 PI3K/Akt/mTOR信号通路表观遗传代谢凋亡免疫与炎症细胞骨架 ERK Akt ROS PPAR PI3K PKC TNF Inhibitor inhibitor inhibit

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