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Cyromazine

Catalog No. T0845 CAS 66215-27-8

Synonyms: CGA-72662, Cyromazin

Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Cyromazine, CAS 66215-27-8

Pack Size	Availability	Price/USD
100 mg	In stock	$ 47.00
200 mg	In stock	$ 58.00
500 mg	In stock	$ 92.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.18%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Cyromazine (CGA-72662) is an ectoparasiticide. Insect growth regulator. Specific activity against dipterous larvae. Cyromazine is a fda approved for use in livestock.
In vitro	In both plants and animals, Cyromazine undergoes dealkylation metabolism and, through environmental degradation, forms melamine.
In vivo	Cyromazine may act at certain stages of cuticle sclerotization, with little to no effect on dihydrofolate reductase and the activity of aminomethylphosphonic acid. It alters the percentage or total content of phenylalanine and tyrosine amino acids in the pupal exoskeleton cuticle, resulting in larvae exhibiting typical signs of Cyromazine intoxication. The mechanism of action likely involves inhibiting the synthesis of chitin and scleroprotein.

Synonyms	CGA-72662, Cyromazin
Molecular Weight	166.18
Formula	C6H10N6
CAS No.	66215-27-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: 1 mg/mL (6.01 mM)

Ethanol: 2 mg/mL (12.03 mM)

DMSO: 31 mg/mL (186.5 mM)

References and Literature

1. Bel Y, et al. Arch Insect Biochem Physiol, 2000, 45(2), 69-78. 2. Beilstein P, et al. J. Agric. Food Chem., 1981, 29 (6), 1132-1135.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Parasitic Compound Library Drug Repurposing Compound Library Natural Product Library for HTS Toxic Compound Library Anti-infective Natural Product Library FDA-Approved & Pharmacopeia Drug Library Bioactive Compound Library RO5 Drug-like Natural Product Library Immunology/Inflammation Compound Library Approved Drug Library

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Cyromazine 66215-27-8 Metabolism Others Endogenous Metabolite CGA72662 Inhibitor inhibit CGA-72662 CGA 72662 Cyromazin inhibitor

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