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Hispidin

🥰Excellent
Catalog No. T7792Cas No. 555-55-5

Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties

Hispidin

Hispidin

🥰Excellent
Purity: 99.55%
Catalog No. T7792Cas No. 555-55-5
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$197In Stock
10 mg$313In Stock
25 mg$562In Stock
50 mg$787In Stock
100 mg$1,070In Stock
1 mL x 10 mM (in DMSO)$217In Stock
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Purity:99.55%
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Product Introduction

Bioactivity
Description
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties
In vitro
Hispidin from P. linteus exhibited quenching effects against DPPH radicals, superoxide radicals, and hydrogen peroxide in a dose-dependent manner. Intracellular reactive oxygen species scavenging activity of hispidin was approximately 55% at a concentration of 30 μM. In addition, hispidin was shown to inhibit hydrogen peroxide-induced apoptosis and increased insulin secretion in hydrogen peroxide-treated cells. These combined results indicate that hispidin may act as an antidiabetic and that this property occurs through preventing β-cells from the toxic action of reactive oxygen species in diabetes[1].Hispidin inhibits protein kinase C β (PKCβ ; IC50 = 2 μM) with no activity against alkaline phosphatase[2]
Chemical Properties
Molecular Weight246.22
FormulaC13H10O5
Cas No.555-55-5
SmilesOc1cc(=O)cc(\C=C\c2ccc(O)c(O)c2)o1
Relative Density.1.657 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 22.5 mg/mL (91.38 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0614 mL20.3070 mL40.6141 mL203.0704 mL
5 mM0.8123 mL4.0614 mL8.1228 mL40.6141 mL
10 mM0.4061 mL2.0307 mL4.0614 mL20.3070 mL
20 mM0.2031 mL1.0154 mL2.0307 mL10.1535 mL
50 mM0.0812 mL0.4061 mL0.8123 mL4.0614 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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