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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9582 | CLEFMA | NF-κB | |
CLEFMA has anti-proliferative activity. CLEFMA inhibits tumor growth associated with NF-κB-regulated anti-inflammatory and anti-metastatic effects. | |||
T38699 | Piperafizine A | ||
Piperafizine A is isolated from Streptoverticillium aspergilloides and potentiates vincristine antitumor potency. | |||
TQ0219 | MK-8033 | c-Met/HGFR | |
MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met). | |||
T6540 | Ibuprofen Lysine | Neoprofen | COX |
Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug. | |||
T8710 | MSAB | Wnt/beta-catenin | |
MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. | |||
T1394 | Ibuprofen | Brufen,(±)-Ibuprofe,Motrin,Advil | COX |
Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu... | |||
T4985 | Neticonazole Hydrochloride | Antifungal | |
Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes. | |||
T8432 | ASP4132 | AMPK | |
ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity. | |||
T12150 | N-Methylbenzamide | PDE | |
N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity. | |||
T6400 | AZD3514 | Androgen Receptor | |
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1. | |||
T11284 | FIDAS-3 | Others , Wnt/beta-catenin , Methionine Adenosyltransferase (MAT) | |
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ... | |||
T11285 | FIDAS-5 | Others | |
FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities. | |||
T4325 | COTI-2 | COTI 2,COTI2 | Apoptosis , p53 |
COTI-2, an orally available thiosemicarbazone, is an activator of mutant forms of the p53 protein with potential antineoplastic activity. | |||
T12997 | SR-318 | p38 MAPK , TNF | |
SR-318 is a potent and highly selective inhibitor of p38 MAPK(IC50s of 5 nM, 32 nM and 6.11 μM for p38α, p38β and p38α/β, respectively), has anti-cancer and anti-inflammatory activity. | |||
T10270 | BAY 2416964 | Aryl Hydrocarbon Receptor | |
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist(example 192, IC50: 341 nM). It has the potential for cancer treatment. | |||
TP2333 | Cyclo(L-Pro-L-Tyr) | Others | |
Maculosin is a secondary metabolite of fungi and bacteria. | |||
T4425 | JK-P3 | VEGFR | |
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format... | |||
T21806 | HNHA | HDAC | |
HNHA is an inhibitor of HDAC. | |||
T8765 | IGOT1-01 | Others | |
iGOT1-01 is an effective inhibitor of glutamate oxaloacetate transaminase 1(GOT1) . iGOT1-01 has IC50s of 84.6 μM and 11.3 μM in GOT1/MDH1 assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 can be used in anti-cancer ... | |||
T0797 | Cimetidine | SKF-92334 | Histamine Receptor |
Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEP... | |||
T0380 | Bicalutamide | ICI-176334 | Androgen Receptor , Autophagy |
Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens. | |||
T11793 | KY-05009 | Wnt/beta-catenin | |
KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity o... | |||
T9211 | Mito-LND | Mito-Loidamine | OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy |
Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation. | |||
T2343 | AS601245 | JNK | |
AS601245 is an inhibitor of the c-Jun NH2-terminal kinase (JNK), with neuroprotective properties. | |||
T9622 | MF-766 | Prostaglandin Receptor | |
MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. It behaves as a full antagonist with an IC50 of 1.4 nM (shifted to 1.8 nM in the presence of 10% HS) in the functional assay. It... | |||
T5125 | LY3200882 | TGF-beta/Smad | |
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). | |||
T14505 | BAY-524 | Others | |
BAY-524 is an inhibitor of Bub1(IC50 = 450 nM.human Bub1 in the presence of 2 mM ATP). | |||
T11529 | H3B-120 | Others , Potassium Channel | |
H3B-120 is a highly selective, competitive, and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor (IC50: 1.5 μM; Ki: 1.4 μM) with anti-cancer activity. | |||
T24706 | RBC10 | RBC 10,RBC-10 | GTPase |
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines. | |||
T8310 | MMP-9-IN-1 | MMP | |
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9). | |||
T7835 | CM10 | CM 10 | Dehydrogenase |
CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor. | |||
T6207 | SC144 | Apoptosis , Interleukin | |
SC144 is an orally active small-molecule gp130 inhibitor. | |||
T8308 | NL-1 | Mitochondrial Metabolism , Autophagy | |
NL-1 is a mitoNEET inhibitor with antileukemic effect. | |||
T6275 | Obatoclax Mesylate | Obatoclax,GX15-070 | BCL , Parasite , Autophagy |
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3. | |||
T2345 | PTC-209 | PTC209,PTC 209 | BMI-1 , Autophagy |
PTC-209 is a potent and selective BMI-1 inhibitor. | |||
T34603 | L-Selenocystine | L-Selenocystine | Others |
L-Selenocystine (L-Selenocystine) can be used as a building block in biologically active selenol compounds. | |||
T12642L | Simurosertib | TAK-931 | CDK |
Simurosertib (TAK-931) is a selective and ATP-competitive cell division cycle 7 kinase inhibitor (IC50: <0.3 nM). | |||
T7698 | BS194 | CDK | |
BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor. | |||
T1995 | Fedratinib | TG-101348,SAR 302503 | Apoptosis , FLT , c-RET , JAK |
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3. | |||
T2029 | Bohemine | ERK , CDK | |
Bohemine is a cyclin-dependent kinase inhibitor. | |||
T9497 | Niraparib tosylate monohyrate | PARP | |
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting... | |||
T2301 | SB 202190 | FHPI,SB202190 | Apoptosis , p38 MAPK , Autophagy |
SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i... | |||
T60024 | CFT7455 | Cemsidomide | Ligand for E3 Ligase |
CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZ... | |||
T4552 | Fursultiamine | Diteftin,Judolor,Alinamin F | Others |
Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency. | |||
T9705 | TL-895 | BTK | |
TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM. | |||
T9595 | LP-261 | Microtubule Associated | |
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. | |||
T8656 | CAY10404 | 3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T | Apoptosis , Akt , COX |
CAY10404 (3-(4-METHYLSULPHONYLPHENYL)-4-PHENYL-5-T) is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSC-LC cel... | |||
T7611 | ODM-203 | VEGFR , FGFR | |
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity | |||
T3278 | Piribedil | EU-4200,Trivastan,ET-495,Trivastal | Dopamine Receptor , Histone Methyltransferase , Adrenergic Receptor |
Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease. | |||
T6335 | Tie2 kinase inhibitor 1 | Tie2 kinase inhibitor | Tie-2 |
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor), an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 μM, which is 200-fold more effective than p38. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN7020 | Astragenol | Others | |
Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research. | |||
T6S0139 | Neobavaisoflavone | Apoptosis , DNA/RNA Synthesis | |
1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si... | |||
T11366 | Garcinol | Apoptosis , Endogenous Metabolite , Histone Acetyltransferase , AChR , AChE | |
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone... | |||
TN2082 | Pinostrobin | Beta Amyloid , IL Receptor , Serine/threonin kinase , TNF | |
Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα²(25-35)-induced neurotoxicity in PC12 cells, at least in part, via inhibiting oxidative damage and calcium overload, as well as suppress... | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
T3866 | Macelignan | Anwuligan,(+)-Anwulignan | Others , COX |
Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. | |||
T5712 | Zerumbone | Antioxidant , HSV | |
Zerumbone is a natural monocyclic sesquiterpene first isolated from rhizomes of the wild ginger Z. zerumbet.It has also been shown to have anti-oxidant and anti-inflammatory activities, contributing to immunomodulatory a... | |||
TN2883 | 3',4'-Dimethoxyflavone | Others , PARP | |
3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities. | |||
TN2054 | Periplocymarin | Calcium Channel | |
Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca. | |||
T0724 | Formononetin | Biochanin B,Flavosil,Formononetol | Apoptosis , FGFR |
Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus. | |||
T2780 | Catalpol | Catalpinoside,Digitalis purpurea L | Others , HBV |
Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects. | |||
T7792 | Hispidin | Endogenous Metabolite , PKC | |
Hispidin is a polyphenol originally, including antioxidant, anti-inflammatory, and cytoprotective properties | |||
T4518 | Licochalcone D | ERK , NF-κB | |
Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect... | |||
T4S1999 | Valepotriate | Valtrate | Apoptosis , HIV Protease |
Valepotriate (Valtrate) fraction can have sedative effects and affect behavioral parameters related to recognition memory. Valepotriates, a new class of cytotoxic and antitumor agents, they are very potent cytotoxic agen... | |||
TN1493 | Chrysosplenol D | IL Receptor , NF-κB , JNK | |
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials. | |||
T5755 | Aloesin | Tyrosinase | |
Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin. | |||
T6569 | Mimosine | Leucenine,NSC 69188,Leucenol,L-Mimosine | Others |
L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator. | |||
T6917 | Oleuropein | Apoptosis , Aromatase , ROS , PPAR | |
Oleuropein is an antioxidant polyphenol isolated from olive leaf. | |||
TN1465 | Cannabigerol | NOS , 5-HT Receptor , ROS | |
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur... | |||
T13229 | Tunicamycin | Influenza Virus , Antibacterial , Antibiotic , Antifungal | |
Tunicamycin is a mixture of antibiotics that inhibit N-linked glycosylation by blocking GlcNAc phosphotransferase (GPT). Tunicamycin has antitumor activity, as well as anti-bacterial, anti-fungal, and anti-viral activity... | |||
TN2269 | Tetramethylcurcumin | Apoptosis , STAT | |
Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and e... | |||
T2899 | Liquiritin | Liquiritigenin-4'-O-glucoside,Liquiritoside | Reactive Oxygen Species |
Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities. | |||
TN1788 | Isookanin | Amylase | |
Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml). | |||
T2217 | Cephalomannine | Baccatin III | Microtubule Associated |
Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity. | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
T7024 | Qingyangshengenin | Qingyangshengenin A,Cynanchagenin | Others |
Qingyangshengenin (Cynanchagenin) is a steroid used in the preparation of antiepileptic agents. | |||
TN1237 | 3-O-Methylgallic acid | 3,4-Dihydroxy-5-methoxybenzoic acid | Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT |
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ... | |||
T2950 | Schisandrin | Wuweizi alcohol-A,Wuweizichun-A,Schizandrol-A,Schizandrol | Autophagy |
Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects. | |||
T3739 | 2,6-Dimethoxyquinone | 2,6-Dimethoxy-1,4-benzoquinone,2,6-Dimethoxy-p-benzoquinone,2,6-Dimethoxybenzoquinone | Others |
2,6-Dimethoxyquinone (2,6-Dimethoxy-p-benzoquinone) is a member of the class of compounds known as P-benzoquinones. 2,6-Dimethoxyquinone is slightly soluble (in water) and an extremely weak basic (essentially neutral) co... | |||
T2895 | Lupeol | Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol | Apoptosis , Androgen Receptor , Akt |
Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity. | |||
T8293 | γ-Tocopherol | (+)-γ-Tocopherol | COX |
(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils. | |||
T3416 | Aucubin | Aucuboside,Rhinanthin | IL Receptor , NF-κB , Antibacterial |
Aucubin (Rhinanthin) is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities. | |||
TN1926 | Methyl caffeate | Methyl caffeate acid | Others , Antibacterial |
Methyl caffeate (Methyl caffeate acid) acid | |||
TN2064 | Physcion 8-O-β-D-glucopyranoside | Physcion 8-O-beta-D-monoglucoside | TNF |
Physcion 8-O-β-D-glucopyranoside (Physcion 8-O-beta-D-monoglucoside) has anti-inflammatory and anti-cancer activities. Physcion 8-O-β-D-glucopyranoside can be used in studies about common malignancy cancer. | |||
T5S1923 | Schisandrin C | Schizandrin-C,Wuweizisu-C | Apoptosis , Others , Virus Protease |
Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells. | |||
T3248 | Alpha-Boswellic acid | α-Boswellic acid | Others |
alpha-Boswellic acid (α-Boswellic acid) is a pentacyclic triterpenoid natural product extracted from frankincense and has anticonvulsant and anticancer effects. In animals, it prevents and reduces Alzheimer's disease mar... | |||
T2S1158 | 4,5-Dicaffeoylquinic acid | 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C | Others , HBV , Endogenous Metabolite |
1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity. | |||
T3673 | Mollugin | Rubimaillin | HER , JAK |
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr... | |||
T0132 | Etoposide | VP-16,VP-16-213 | Apoptosis , Mitophagy , Topoisomerase , Antibacterial , Antibiotic , Autophagy |
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy. | |||
T5S1058 | Triptonide | PG 492,NSC 165677 | Apoptosis , Wnt/beta-catenin , Autophagy |
1. Triptonide (PG 492) is effective in the treatment of autoimmune diseases and has potent antileukemic and antitumor activities. 2. Triptonide possesses anti-inflammatory activity, upregulate the expression of IL-37, an... | |||
T2882 | Genistin | Genistoside,Genistein glucoside,Genistein 7-glucoside,Genistine,Genistein 7-O-β-D-glucopyranoside | Apoptosis , Estrogen Receptor/ERR , Others |
Genistin (Genistoside) is the major isoflavonoid of soybeans and soy products.It has been reported to possess various therapeutic effects, including anti-inflammatory and anticancer activities | |||
T3P2904 | α-Linolenic acid | Alpha-Linolenic Acid,Linolenic acid | Akt , PI3K |
α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland... | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
T2870 | Matrine | Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine | Mitophagy , Ferroptosis , Opioid Receptor , Autophagy |
Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist. | |||
T2S2104 | Sinigrin hydrate | Sinigrin monohydrate,Allylglucosinolate monohydrate | Antibacterial |
Sinigrin hydrate (Allylglucosinolate monohydrate) has antimicrobial activity. Sinigrin hydrate (Allylglucosinolate monohydrate) exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in... | |||
T2S0618 | β-Elemonic Acid | 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid | Apoptosis , Reactive Oxygen Species , COX |
β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel... | |||
TN1143 | 1-O-Acetyl britannilactone | NF-κB , COX | |
1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. | |||
TN1579 | Dihydrocucurbitacin B | 23,24-dihydrocucurbitacin B | IL Receptor , TNF , COX |
Dihydrocucurbitacin B (23,24-dihydrocucurbitacin B) is isolated from the roots of Cayaponia tayuya with anti-cancer activity. | |||
TN1142 | 8-Oxocoptisine | 8-Oxycoptisine | Others |
8-Oxocoptisine (8-Oxycoptisine) is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer | |||
TQ0185 | 14-Deoxy-11,12-didehydroandrographolide | AP10,14-dehydro Andrographolide | NF-κB |
14-Deoxy-11,12-didehydroandrographolide (AP10) has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03156 | VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) | Mouse,Rat | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei... | |||
TMPY-01007 | VEGFC Protein, Human, Recombinant (His) | Human | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei... | |||
TMPY-01884 | MMP-8 Protein, Human, Recombinant | Human | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-01431 | L1CAM Protein, Human, Recombinant (His) | Human | HEK293 |
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai... | |||
TMPY-02778 | ENPP2 Protein, Human, Recombinant (His) | Human | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-00463 | ENPP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen... | |||
TMPY-00566 | CCL18 Protein, Human, Recombinant (His) | Human | Yeast |
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its... | |||
TMPY-02848 | Adiponectin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPY-05556 | Adiponectin Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other t... | |||
TMPY-01478 | HSP90 alpha Protein, Human, Recombinant | Human | E. coli |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... | |||
TMPY-00834 | IGF1R/CD221 Protein, Human, Recombinant (His) | Human | HEK293 |
The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide... | |||
TMPY-00904 | Urokinase/uPA Protein, Human, Recombinant (His) | Human | HEK293 |
Plasminogen activator, urokinase, also known as PLAU and uPA, is a serine protease which converts plasminogen to plasmin, a broad-spectrum protease active on extracellular matrix (ECM) components. It is involved in compl... | |||
TMPY-05446 | CD200 Protein, Human, Recombinant (hFc) | Human | HEK293 |
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ... | |||
TMPY-02219 | Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His) | H1N1 | E. coli |
The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N... | |||
TMPY-02431 | BCL-XL Protein, Human, Recombinant (His) | Human | E. coli |
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi... | |||
TMPK-00906 | PSCA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPK-00728 | PSCA Protein, Human, Recombinant (hFc) | Human | HEK293 |
Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s... | |||
TMPK-01248 | CXCL4 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a... | |||
TMPK-00013 | CXCL4 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a... | |||
TMPY-04936 | BCL2A1 Protein, Human, Recombinant (His) | Human | E. coli |
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in... | |||
TMPK-00014 | CXCL4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a... | |||
TMPK-00012 | CXCL4 Protein, Human, Recombinant (His & Avi) | Human | E. coli |
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a... | |||
TMPK-00491 | IL-18BP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin... | |||
TMPK-00492 | IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated | Cynomolgus | HEK293 |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin... | |||
TMPY-04916 | RGMB Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig... | |||
TMPK-00082 | IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggestin... | |||
TMPY-04906 | RGMB Protein, Human, Recombinant (His) | Human | HEK293 |
RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig... | |||
TMPY-04480 | UMP-CMP kinase/CMPK1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), re... | |||
TMPY-01561 | PIG3 Protein, Human, Recombinant (His) | Human | E. coli |
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of ca... | |||
TMPY-04133 | UNC5B Protein, Human, Recombinant (His) | Human | HEK293 |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPK-00170 | CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated | Human | HEK293 |
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstr... | |||
TMPY-00507 | UNC5B Protein, Human, Recombinant (hFc) | Human | HEK293 |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPY-04003 | UNC5B Protein, Rat, Recombinant (hFc) | Rat | HEK293 |
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ... | |||
TMPK-00456 | IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated | Human | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot... | |||
TMPK-00658 | IGF1R/CD221 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot... | |||
TMPK-00455 | IGF1R/CD221 Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot... | |||
TMPK-00336 | GPC3 Protein-VLP, Human, Recombinant | Human | E. coli |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ... | |||
TMPY-03416 | TNFAIP8 Protein, Human, Recombinant (His) | Human | E. coli |
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al... | |||
TMPK-00337 | GPC3 Protein-VLP, Human, Recombinant (aa 438-554) | Human | HEK293 |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 ... | |||
TMPY-00520 | MMP-8 Protein, Mouse, Recombinant (His) | Mouse | CHO |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-01844 | MMP-8 Protein, Mouse, Recombinant | Mouse | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-01377 | MMP-8 Protein, Human, Recombinant (His) | Human | HEK293 |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... | |||
TMPY-03155 | VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) | Mouse,Rat | HEK293 |
Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei... | |||
TMPK-01137 | FAM3D Protein, Human, Recombinant (hFc) | Human | HEK293 |
The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m... | |||
TMPH-01878 | PODXL Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte ... | |||
TMPY-04203 | RAB1B Protein, Human, Recombinant (hFc) | Human | HEK293 |
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC ... | |||
TMPH-01877 | PODXL Protein, Human, Recombinant (His) | Human | Yeast |
Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte ... | |||
TMPY-06759 | L1CAM Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai... | |||
TMPY-06857 | L1CAM Protein, Human, Recombinant (hFc) | Human | HEK293 |
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai... | |||
TMPY-06796 | L1CAM Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
L1 cell adhesion molecule (L1CAM), also designated as CD171, is a cell adhesion receptor of the immunoglobulin superfamily, known for its roles in nerve cell function. While originally believed to be present only in brai... | |||
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Cat No. | Product Name | ||
---|---|---|---|
L2100 | Anti-Cancer Compound Library | 7360 compounds | |
A unique collection of 7360 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2150 | Anti-Cancer Drug Library | 3159 compounds | |
A unique collection of 3159 anticancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2191 | Anti-Breast Cancer Compound Library | 1965 compounds | |
A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study; | |||
L2190 | Anti-Lung Cancer Compound Library | 1735 compounds | |
A unique collection of 1735 compounds with anti-lung cancer therapeutic activity or targeting lung cancer’s major signaling pathways, can be used for anti-lung cancer drug discovery and mechanism study; | |||
L2192 | Anti-Pancreatic Cancer Compound Library | 2267 compounds | |
A unique collection of 2267 pancreatic cancer related compounds can be used in HTS and HCS; | |||
L2180 | Anti-Cancer Compound Library Plus | 1468 compounds | |
Well-chosen 1468 anti-tumor compounds with unique structures; | |||
L2160 | Anti-Cancer Active Compound Library | 3250 compounds | |
A unique collection of 3250 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L2110 | Anti-Cancer Approved Drug Library | 1825 compounds | |
A unique collection of 1825 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS); | |||
L2120 | Anti-Cancer Clinical Compound Library | 2614 compounds | |
A unique collection of 2614 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L2130 | Anti-Cancer Metabolism Compound Library | 1280 compounds | |
A unique collection of 1280 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); | |||
L2193 | Anti-Liver Cancer Compound Library | 1816 compounds | |
1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies. | |||
L2195 | Anti-Prostate Cancer Compound Library | 2096 compounds | |
2096 compounds associated with prostate cancer that can be used for high-throughput and high-content screening. | |||
L2196 | Anti-Ovarian Cancer Compound Library | 1888 compounds | |
A unique collection of 1888 compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological study; | |||
L2194 | Anti-Colorectal Cancer Compound Library | 1565 compounds | |
1565 compounds associated with colorectal cancer that can be used for high-throughput and high-content screening. | |||
L6740 | Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library | 386 compounds | |
A collection of 386 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies. | |||
L6100 | Polyphenolic Natural Product Library | 640 compounds | |
A unique collection of 640 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L9000 | Apoptosis Compound Library | 1796 compounds | |
A unique collection of 1796 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; | |||
L6110 | Alkaloid Natural Product Library | 468 compounds | |
A unique collection of 468 natural alkaloids can be used for high throughput and high content screening; | |||
L6200 | The Yao nationality medicine Library | 225 compounds | |
A collection of 225 natural product molecules originated from Yao medicine, which can be used for high-throughput and high-content screening. | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; | |||
L6810 | Traditional Chinese Medicine Monomer Library | 2771 compounds | |
A unique collection of 2771 compounds (TCM monomers) sourcing from traditional Chinese Medicines, is a powerful tool for drug discovery and research in mechanism; | |||
L6130 | Terpene Natural Product Library | 522 compounds | |
A unique collection of 522 natural terpenes and terpenoids can be used for high throughput and high content screening; | |||
L6700 | Anti-Tumor Natural Product Library | 1800 compounds | |
A unique collection of 1800 natural products with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS); | |||
L8100 | Cell Cycle Compound Library | 695 compounds | |
A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); | |||
L6600 | Anti-Gastroenteritis Natural Product Library | 223 compounds | |
A unique collection of 223 natural products related to gastroenteritis for high throughput screening (HTS) and high content screening (HCS); | |||
L5510 | Drug-induced Liver Injury (DILI) Compound Library | 1040 compounds | |
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening; | |||
L9600 | Peptide Compound Library | 800 compounds | |
800 peptides can be used in peptide drug development and signaling transduction and mechanism study; | |||
L6500 | Microbial Natural Product Library | 560 compounds | |
A unique collection of 560 microbial natural products for high throughput screening (HTS) and high content screening (HCS); |