Shopping Cart

Remove All

Your shopping cart is currently empty

Atg4B-IN-2

Select Batch

Purity:98.86%

Resource Download

COA HPLC HNMR

Atg4B-IN-2

Catalog No. T60967Cas No. 2765008-88-4

Atg4B-IN-2 is a potent and selective Atg4B inhibitor with anticancer activity that inhibits the activity of Atg4B and PLA2.Atg4B-IN-2 resists the anticancer activity of anti-desiccation-resistant prostate cancer drugs through autophagy.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
1 mg	$115	In Stock
5 mg	$228	In Stock
10 mg	$380	In Stock
25 mg	$685	In Stock
50 mg	$998	In Stock
100 mg	$1,500	In Stock

Bulk & Custom

Add to Cart

Questions

Related Compound Libraries of "Atg4B-IN-2"

Product Introduction

Bioactivity

Description

In vitro

In a dose-dependent manner, Atg4B-IN-2 (compound 21f) (1-10 μM; 2 hours) restores p62 expression in cells treated with amino acid-free (AF) conditions [1].
At concentrations of 1 and 5 μM (2 hours), Atg4B-IN-2 moderately decreases autophagic vesicles at 1 μM and almost completely inhibits autophagy at 5 μM [1].
At a concentration of 5 μM (2 hours), Atg4B-IN-2 inhibits Abi-induced autophagy, significantly enhances apoptotic cell death, and increases sensitivity to Abi [1].

Chemical Properties

Molecular Weight	330.46
Formula	C21H30O3
Cas No.	2765008-88-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 80 mg/mL (242.09 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0261 mL	15.1304 mL	30.2608 mL	151.3042 mL
5 mM	0.6052 mL	3.0261 mL	6.0522 mL	30.2608 mL
10 mM	0.3026 mL	1.5130 mL	3.0261 mL	15.1304 mL
20 mM	0.1513 mL	0.7565 mL	1.5130 mL	7.5652 mL
50 mM	0.0605 mL	0.3026 mL	0.6052 mL	3.0261 mL
100 mM	0.0303 mL	0.1513 mL	0.3026 mL	1.5130 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Welcome to our new website experience

What's new

Atg4B-IN-2

Atg4B-IN-2