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Soyasapogenol B

🥰Excellent
Catalog No. TN2225Cas No. 595-15-3

Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.

Soyasapogenol B

Soyasapogenol B

🥰Excellent
Purity: 99.81%
Catalog No. TN2225Cas No. 595-15-3
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
Pack SizePriceAvailabilityQuantity
1 mg$34In Stock
5 mg$94In Stock
10 mg$148In Stock
25 mg$251In Stock
50 mg$357In Stock
1 mL x 10 mM (in DMSO)$94In Stock
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Purity:99.81%
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Product Introduction

Bioactivity
Description
Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.
In vitro
Glycyrrhizin showed significant dose-dependent protective effects against the cytotoxicity of t-BuOOH. Among Soyasapogenol B and its glucuronides, the monoglucuronide showed the most potent hepatoprotective activity, followed by Soyasapogenol B itself. Soyasaponin III was weakly protective, while soyasaponin I increased the toxicity of t-BuOOH. Among sophoradiol and its glucuronides, sophoradiol itself showed the most potent hepatoprotective activity, which was equal to glycyrrhizin, while the monoglucuronide and kaikasaponin III showed an increase in cytotoxicity. These results were considerably different from those reported previously on the protective effects of these compounds using primary cultures of immunologically injured rat liver cells[1]
Chemical Properties
Molecular Weight458.72
FormulaC30H50O3
Cas No.595-15-3
Smiles[H][C@@]12CC(C)(C)C[C@@H](O)[C@]1(C)CC[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)[C@](C)(CO)[C@]3([H])CC[C@@]12C
Relative Density.1.10 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (59.95 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1800 mL10.8999 mL21.7998 mL108.9990 mL
5 mM0.4360 mL2.1800 mL4.3600 mL21.7998 mL
10 mM0.2180 mL1.0900 mL2.1800 mL10.8999 mL
20 mM0.1090 mL0.5450 mL1.0900 mL5.4499 mL
50 mM0.0436 mL0.2180 mL0.4360 mL2.1800 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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