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FT113

Catalog No. T7947Cas No. 1630808-89-7

FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity

FT113

FT113

Purity: 97.05%
Catalog No. T7947Cas No. 1630808-89-7
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
Pack SizePriceAvailabilityQuantity
2 mg$33In Stock
5 mg$52In Stock
10 mg$89In Stock
25 mg$198In Stock
50 mg$349In Stock
100 mg$596In Stock
1 mL x 10 mM (in DMSO)$58In Stock
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Purity:97.05%
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Product Introduction

Bioactivity
Description
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity
Targets&IC50
Fas:213 nM
In vivo
FT113, a compound with potent biochemical and cellular activity, which translated into excellent activity in in vivo models.Caused 32 % and 50% tumor growth inhibition at 25 and 50 mg/kg, respectively in mice.
Animal Research
Athymic nude mice bearing MV-411 cells. Dosage:5, 25, or 50 mg/kg, twice daily for 16 days
Chemical Properties
Molecular Weight409.41
FormulaC22H20FN3O4
Cas No.1630808-89-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 62.5 mg/mL (152.66 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4425 mL12.2127 mL24.4254 mL122.1270 mL
5 mM0.4885 mL2.4425 mL4.8851 mL24.4254 mL
10 mM0.2443 mL1.2213 mL2.4425 mL12.2127 mL
20 mM0.1221 mL0.6106 mL1.2213 mL6.1063 mL
50 mM0.0489 mL0.2443 mL0.4885 mL2.4425 mL
100 mM0.0244 mL0.1221 mL0.2443 mL1.2213 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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