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NSC 694623

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Catalog No. T60558Cas No. 907957-34-0

NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 15.9 μM against recombinant HAT p300/CBP-associated factor (PCAF) and exhibits anti-proliferative activity against certain cancer cells, making it useful for anti-cancer research.

NSC 694623

NSC 694623

🥰Excellent
Purity: 99.87%
Catalog No. T60558Cas No. 907957-34-0
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 15.9 μM against recombinant HAT p300/CBP-associated factor (PCAF) and exhibits anti-proliferative activity against certain cancer cells, making it useful for anti-cancer research.
Pack SizePriceAvailabilityQuantity
1 mg40 €In Stock
5 mg93 €In Stock
10 mg140 €In Stock
25 mg282 €In Stock
50 mg527 €In Stock
100 mg743 €In Stock
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Purity:99.87%
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Product Introduction

Bioactivity
Description
NSC 694623 is a potent histone acetyltransferase (HAT) inhibitor with an IC50 of 15.9 μM against recombinant HAT p300/CBP-associated factor (PCAF) and exhibits anti-proliferative activity against certain cancer cells, making it useful for anti-cancer research.
Targets&IC50
PCAF:15.9 μM
In vitro
NSC 694623 exhibits antiproliferative activity against SK-N-SH cells, with an IC50 value of 8.93 μM. Additionally, it inhibits 21% of HCT116 cells at a concentration of 25 μM.[1]
Chemical Properties
Molecular Weight284.38
FormulaC16H16N2OS
Cas No.907957-34-0
SmilesO=C1N(SC=2C1=CC=CN2)C3=CC=C(CCCC)C=C3
Storage & Solubility Information
StorageShipping with blue ice.
Solubility Information
DMSO: 112.5 mg/mL (395.6 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.5164 mL17.5821 mL35.1642 mL175.8211 mL
5 mM0.7033 mL3.5164 mL7.0328 mL35.1642 mL
10 mM0.3516 mL1.7582 mL3.5164 mL17.5821 mL
20 mM0.1758 mL0.8791 mL1.7582 mL8.7911 mL
50 mM0.0703 mL0.3516 mL0.7033 mL3.5164 mL
100 mM0.0352 mL0.1758 mL0.3516 mL1.7582 mL

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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