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Remodelin hydrobromide

Catalog No. T6133Cas No. 1622921-15-6
Alias Remodelin HBR, Remodelin

Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.

Remodelin hydrobromide

Remodelin hydrobromide

Purity: 99.84%
Catalog No. T6133Alias Remodelin HBR, RemodelinCas No. 1622921-15-6
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
Pack SizePriceAvailabilityQuantity
5 mg$52In Stock
10 mg$79In Stock
25 mg$148In Stock
50 mg$262In Stock
100 mg$392In Stock
200 mg$575In Stock
500 mg$886In Stock
1 mL x 10 mM (in DMSO)$58In Stock
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Purity:99.84%
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Product Introduction

Bioactivity
Description
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
In vivo
Remodelin restores nuclear morphology and enhances the resilience of the nucleus in HGPS cells by depleting LMNA through microtubule reorganization, mediated by its inhibition of NAT10.
AliasRemodelin HBR, Remodelin
Chemical Properties
Molecular Weight363.28
FormulaC15H15BrN4S
Cas No.1622921-15-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 40 mg/mL (110.11 mM), Sonication is recommended.
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7527 mL13.7635 mL27.5270 mL137.6349 mL
5 mM0.5505 mL2.7527 mL5.5054 mL27.5270 mL
10 mM0.2753 mL1.3763 mL2.7527 mL13.7635 mL
20 mM0.1376 mL0.6882 mL1.3763 mL6.8817 mL
50 mM0.0551 mL0.2753 mL0.5505 mL2.7527 mL
100 mM0.0275 mL0.1376 mL0.2753 mL1.3763 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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