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3-O-Methylgallic acid
🥰Excellent
Catalog No. TN1237Cas No. 3934-84-7
Alias 3,4-Dihydroxy-5-methoxybenzoic acid
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells (IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. It inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1, which are known to be activated in colorectal cancer.
3-O-Methylgallic acid
🥰Excellent
Purity: 98.53%
Catalog No. TN1237Alias 3,4-Dihydroxy-5-methoxybenzoic acidCas No. 3934-84-7
3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells (IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. It inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1, which are known to be activated in colorectal cancer.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $30 | In Stock | |
| 500 mg | $64 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $50 | In Stock |
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CitedSelect Batch
Purity:98.53%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells (IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation in the gut. It inhibits transcription factors NF-κB, AP-1, STAT-1, and OCT-1, which are known to be activated in colorectal cancer. |
| Targets&IC50 | Cell proliferation:24.1 μM(Caco-2 cells) |
| In vitro | 3,4-Dihydroxy-5-methoxybenzoic acid(10-100 μM) caused a time- and dose-dependent decrease in cell viability[1]. |
| Alias | 3,4-Dihydroxy-5-methoxybenzoic acid |
| Molecular Weight | 184.15 |
| Formula | C8H8O5 |
| Cas No. | 3934-84-7 |
| Smiles | COc1cc(cc(O)c1O)C(O)=O |
| Relative Density. | 1.499 g/cm3 at 20℃ |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 37.5 mg/mL (203.64 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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