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Busulfan-d8

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Catalog No. TMID-0076Cas No. 116653-28-2
Alias Sulphabutin-d8, Myleran-d8, Busulphan-d8

Busulfan-d8 (Sulphabutin-d8) is a deuterated Busulfan. Busulfan is an effective alkylating anticancer agent with immunosuppressive and myeloablative activities. It exerts anti-cancer activity by crosslinking DNA and causing DNA damage.

Busulfan-d8

Busulfan-d8

😃Good
Catalog No. TMID-0076Alias Sulphabutin-d8, Myleran-d8, Busulphan-d8Cas No. 116653-28-2
Busulfan-d8 (Sulphabutin-d8) is a deuterated Busulfan. Busulfan is an effective alkylating anticancer agent with immunosuppressive and myeloablative activities. It exerts anti-cancer activity by crosslinking DNA and causing DNA damage.
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1 mg$627-10 days
5 mg$222In Stock
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Product Introduction

Bioactivity
Description
Busulfan-d8 (Sulphabutin-d8) is a deuterated Busulfan. Busulfan is an effective alkylating anticancer agent with immunosuppressive and myeloablative activities. It exerts anti-cancer activity by crosslinking DNA and causing DNA damage.
AliasSulphabutin-d8, Myleran-d8, Busulphan-d8
Chemical Properties
Molecular Weight254.35
FormulaC6H6D8O6S2
Cas No.116653-28-2
SmilesO(S(C)(=O)=O)C(C(C(C(OS(C)(=O)=O)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H]
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMF: 10 mg/mL (39.32 mM), Sonication is recommended.
DMSO: 10 mg/mL (39.32 mM), Sonication is recommended.
Solution Preparation Table
DMF/DMSO
1mg5mg10mg50mg
1 mM3.9316 mL19.6580 mL39.3159 mL196.5795 mL
5 mM0.7863 mL3.9316 mL7.8632 mL39.3159 mL
10 mM0.3932 mL1.9658 mL3.9316 mL19.6580 mL
20 mM0.1966 mL0.9829 mL1.9658 mL9.8290 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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