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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $61 | In Stock | |
25 mg | $126 | In Stock | |
50 mg | $216 | In Stock | |
100 mg | $324 | In Stock | |
1 mL x 10 mM (in DMSO) | $41 | In Stock |
Description | NL-1, a mitoNEET inhibitor, exhibits antileukemic effects. |
In vitro | NL-1 Reduced the number of viable cells in REH, REH/Ara-C and ALL (SUP-B15, TOM-1, JM1, NALM-1, NALM-6, BV-173) cell lines, in a concentration-dependent manner. |
In vivo | NL-1 showed antileukemic activity in an in vivo mouse ALL model |
Cell Research | Cell Line:REH, REH/Ara-C and ALL (SUP-B15, TOM-1, JM1, NALM-1, NALM-6, BV-173) cell lines. Concentration:10 μM, 20 μM, 30 μM, 40 μM, 50 μM, 60 μM, 70 μM, 80 μM, 100 μM.Incubation Time:72 hours |
Animal Research | Animal Model:10 female NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice (6-8 month old) injected with TOM-1 ALL cells. Dosage:10 mg/kg.Administration:Intraperitoneal injection; daily; for 5 days |
Molecular Weight | 335.46 |
Formula | C18H25NO3S |
Cas No. | 188532-26-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (745.25 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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