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rac-CCT-250863 HCl
😃Good
Catalog No. T28498L
Alias rac-CCT-250863 HCl(1364269-06-6 Free base)
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies.
rac-CCT-250863 HCl
😃Good
Purity: 98.06%
Catalog No. T28498LAlias rac-CCT-250863 HCl(1364269-06-6 Free base)
rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $195 | In Stock | |
| 5 mg | $440 | In Stock | |
| 50 mg | $1,390 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $552 | In Stock |
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Purity:98.06%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | rac-CCT-250863 HCl is a selective and reversible inhibitor of NEK 2. rac-CCT-250863 HCl induces cell cycle arrest and has good anti-proliferative activity against cancer cells. rac-CCT-250863 HCl can be used in combination with Pomalidomide to induce apoptosis and can be used in combined anti-cancer studies. |
| Targets&IC50 | H929 multiple myeloma cell lines:8.0 μΜ, AMOL:7.1 μΜ, K12PE:8.7 μΜ, NEK2:0.073 µM |
| Alias | rac-CCT-250863 HCl(1364269-06-6 Free base) |
| Molecular Weight | 527 |
| Formula | C24H26ClF3N4O2S |
| Smiles | NC1=C(C=C(C=N1)C2=CC(CN(C)C)=CS2)C3=CC(OC(/C=C\C(F)(F)F)C)=C(C(N)=O)C=C3.Cl |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (42.69 mM)  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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