Shopping Cart
- Remove All
- Your shopping cart is currently empty
Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $148 | Backorder | |
5 mg | $387 | Backorder | |
50 mg | Inquiry | Backorder | |
1 mL x 10 mM (in DMSO) | $458 | In Stock |
Description | Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively. |
Targets&IC50 | BChE:7.39 µM , AChE:0.66 µM |
In vitro | Garcinol (10-50 μM; 24-72 hours) induces apoptosis and inhibits the proliferation of HNSCC cells in a time- and dose-dependent manner, specifically in the cell lines CAL27 and UMSCC1. Additionally, Garcinol (50 μM; 1-6 hours) suppresses the phosphorylation and degradation of constitutive IκBα in a time-dependent manner. |
In vivo | Garcinolinduces significant inhibition of tumor growth. |
Molecular Weight | 602.8 |
Formula | C38H50O6 |
Cas No. | 78824-30-3 |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | Ethanol: 20 mg/mL (33.18 mM), Sonication and heating are recommended. DMSO: 20 mg/mL (33.18 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
Ethanol/DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.