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ARP 101

🥰Excellent
Catalog No. T22034Cas No. 849773-63-3
Alias ARP101

ARP 101 is an effective selective matrix metalloproteinase-2 (MMP-2) inhibitor with anti-cancer activity. It induces the inhibition of HCMV through non-classical chelate 1 (SQSTM1)/p62-Keap1-Nrf2 pathways and phosphorylation of the C-terminal domain of p62, regulating autophagy and inhibiting melanogenesis.

ARP 101

ARP 101

🥰Excellent
Purity: 98.26%
Catalog No. T22034Alias ARP101Cas No. 849773-63-3
ARP 101 is an effective selective matrix metalloproteinase-2 (MMP-2) inhibitor with anti-cancer activity. It induces the inhibition of HCMV through non-classical chelate 1 (SQSTM1)/p62-Keap1-Nrf2 pathways and phosphorylation of the C-terminal domain of p62, regulating autophagy and inhibiting melanogenesis.
Pack SizePriceAvailabilityQuantity
1 mg$100In Stock
5 mg$246In Stock
10 mg$396In Stock
25 mg$818In Stock
50 mg$1,250In Stock
100 mg$1,690In Stock
200 mg$2,280In Stock
1 mL x 10 mM (in DMSO)$268In Stock
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Purity:98.26%
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Product Introduction

Bioactivity
Description
ARP 101 is an effective selective matrix metalloproteinase-2 (MMP-2) inhibitor with anti-cancer activity. It induces the inhibition of HCMV through non-classical chelate 1 (SQSTM1)/p62-Keap1-Nrf2 pathways and phosphorylation of the C-terminal domain of p62, regulating autophagy and inhibiting melanogenesis.
AliasARP101
Chemical Properties
Molecular Weight406.5
FormulaC20H26N2O5S
Cas No.849773-63-3
SmilesN([C@@H](C(NO)=O)C(C)C)(S(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2)OC(C)C
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (196.8 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4600 mL12.3001 mL24.6002 mL123.0012 mL
5 mM0.4920 mL2.4600 mL4.9200 mL24.6002 mL
10 mM0.2460 mL1.2300 mL2.4600 mL12.3001 mL
20 mM0.1230 mL0.6150 mL1.2300 mL6.1501 mL
50 mM0.0492 mL0.2460 mL0.4920 mL2.4600 mL
100 mM0.0246 mL0.1230 mL0.2460 mL1.2300 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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