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Ganoderic acid Y
Catalog No. TN1668Cas No. 86377-52-8
Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.
Ganoderic acid Y
Catalog No. TN1668Cas No. 86377-52-8
Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $890 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $900 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating. |
| In vitro | Here, we evaluated the antiviral activities of two Ganoderma lucidum triterpenoids (GLTs), Lanosta-7,9(11),24-trien-3-one,15;26-dihydroxy (GLTA) and Ganoderic acid Y (GLTB), against EV71 infection. The results showed that the two natural compounds display significant anti-EV71 activities without cytotoxicity in human rhabdomyosarcoma (RD) cells as evaluated by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) cell proliferation assay. The mechanisms by which the two compounds affect EV71 infection were further elucidated by three action modes using Ribavirin, a common antiviral drug, as a positive control[1] |
| Molecular Weight | 454.68 |
| Formula | C30H46O3 |
| Cas No. | 86377-52-8 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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