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Hulupinic acid
🥰Excellent
Catalog No. TN4228Cas No. 1891-42-5
Hulupinic acid is the main oxidation product of hop acid, which may inhibit the production of NO in macrophages RAW 264.7 cells.
Hulupinic acid
🥰Excellent
Purity: 99.76%
Catalog No. TN4228Cas No. 1891-42-5
Hulupinic acid is the main oxidation product of hop acid, which may inhibit the production of NO in macrophages RAW 264.7 cells.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | 135 € | In Stock | |
| 5 mg | 270 € | In Stock | |
| 10 mg | 378 € | In Stock | |
| 25 mg | 655 € | In Stock | |
| 50 mg | Inquiry | In Stock |
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CitedSelect Batch
Purity:99.76%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Hulupinic acid is the main oxidation product of hop acid, which may inhibit the production of NO in macrophages RAW 264.7 cells. |
| In vitro | The ethyl acetate soluble fraction of hops (Humulus lupulus) showed potent inhibitory activity on the production of nitric oxide (NO) induced by a combination of LPS and IFN-gamma. Four known prenylflavonoids (1-4) and a new prenylflavonoid (5), Hulupinic acid (6), lupulone (7), and its six new derivatives (8-13) were isolated from the active fraction. Their inhibitory activities on the production of NO in macrophage RAW 264.7 cells were examined. Hulupinic acid did not show cytotoxicity (200 µM, cell viability>95%), and no significant inhibitory activity was observed (IC50>100μM).[1] |
| Molecular Weight | 264.32 |
| Formula | C15H20O4 |
| Cas No. | 1891-42-5 |
| Smiles | C(C=C(C)C)C1(CC=C(C)C)C(=O)C(O)=C(O)C1=O |
| Relative Density. | 1.177 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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