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K-252b

Catalog No. T15637 CAS 99570-78-2

K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor. It is effective in inhibiting extracellular kinases in cultured cells due to its inability to freely cross the cell membrane.

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K-252b, CAS 99570-78-2

Pack Size	Availability	Price/USD	Quantity
1 mg	4-5 weeks	$ 838.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	453.45
Formula	C26H19N3O5
CAS No.	99570-78-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Yasuzawa, T., et al. The structures of the novel protein kinase C inhibitors K-252a, b, c AND d Journal of Antibiotics 39(8), 1072-1078 (1986). 2. Plomp, J.J., et al. Involvement of protein kinases in the upregulation of acetylcholine release at endplates of α-bungarotoxin-treated rats Journal of Physiology 493, 175-186 (1996). 3. Zhu, X., et al. Evidence of ectokinase-mediated phosphorylation of osteopontin and bone sialoprotein by osteoblasts during bone formation in vitro Biochemistry Journal 323, 637-643 (1997).

Related Products

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Valrubicin Methyl-Hesperidin Epsilon-V1-2, Cys-conjugated Psychosine CRT0066854 hydrochloride Bisindolylmaleimide I NH125 Bisindolylmaleimide V

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

K-252b 99570-78-2 Chromatin/Epigenetic Cytoskeletal Signaling PKC K252b K 252b inhibitor inhibit

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