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KDM4D-IN-1

Catalog No. T4214Cas No. 2098902-68-0

KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).

KDM4D-IN-1

KDM4D-IN-1

Purity: 100%
Catalog No. T4214Cas No. 2098902-68-0
KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).
Pack SizePriceAvailabilityQuantity
1 mg$70In Stock
5 mg$169In Stock
10 mg$273In Stock
25 mg$549In Stock
50 mg$883In Stock
100 mg$1,290In Stock
1 mL x 10 mM (in DMSO)$187In Stock
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Purity:100%
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Product Introduction

Bioactivity
Description
KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 μM).
Targets&IC50
KDM4D:0.41±0.03 μM
In vitro
KDM4D-IN-1 almost not inhibits KDM2B, KDM3B, and KDM5A (IC50>10 μM), indicating that KDM4D-IN-1 has a good specific for KDM4D against other selected KDMs.
Chemical Properties
Molecular Weight225.21
FormulaC11H7N5O
Cas No.2098902-68-0
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 11 mg/mL (48.84 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.4403 mL22.2015 mL44.4030 mL222.0150 mL
5 mM0.8881 mL4.4403 mL8.8806 mL44.4030 mL
10 mM0.4440 mL2.2202 mL4.4403 mL22.2015 mL
20 mM0.2220 mL1.1101 mL2.2202 mL11.1008 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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