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MC-DOXHZN hydrochloride

Catalog No. TQ0049Cas No. 480998-12-7
Alias Doxorubicin(6-maleimidocaproyl)hydrazone hydrochloride

MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor.

MC-DOXHZN hydrochloride

MC-DOXHZN hydrochloride

Catalog No. TQ0049Alias Doxorubicin(6-maleimidocaproyl)hydrazone hydrochlorideCas No. 480998-12-7
MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor.
Pack SizePriceAvailabilityQuantity
5 mg$22035 days
10 mg$39535 days
25 mg$66035 days
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Product Introduction

Bioactivity
Description
MC-DOXHZN hydrochloride is an albumin-binding prodrug of Doxorubicin. Doxorubicin is a DNA topoisomerase II inhibitor.
AliasDoxorubicin(6-maleimidocaproyl)hydrazone hydrochloride
Chemical Properties
Molecular Weight787.22
FormulaC37H43ClN4O13
Cas No.480998-12-7
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (152.44 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.2703 mL6.3515 mL12.7029 mL63.5146 mL
5 mM0.2541 mL1.2703 mL2.5406 mL12.7029 mL
10 mM0.1270 mL0.6351 mL1.2703 mL6.3515 mL
20 mM0.0635 mL0.3176 mL0.6351 mL3.1757 mL
50 mM0.0254 mL0.1270 mL0.2541 mL1.2703 mL
100 mM0.0127 mL0.0635 mL0.1270 mL0.6351 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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