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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $82 | In Stock | |
5 mg | $197 | In Stock | |
10 mg | $372 | In Stock | |
25 mg | $629 | In Stock | |
50 mg | $896 | In Stock | |
100 mg | $1,220 | In Stock | |
500 mg | $2,450 | In Stock | |
1 mL x 10 mM (in DMSO) | $226 | In Stock |
Description | MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatase-mediated cell migration and has anticancer activity. |
In vitro | MLS000544460 binds to Eya2 ED (dialyzed into 10 μM EDTA to remove Mg2+) with a Kd of 0.80 μM.[1] MLS000544460 (10 μM) inhibits Eya2-mediated cell migration in human Eya2, Eya2 phosphatase-dead (D274N), and YFP (as a negative control) expressing MCF10A cells.[1] |
Molecular Weight | 341.36 |
Formula | C17H12FN3O2S |
Cas No. | 352336-36-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 30 mg/mL (87.88 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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