Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatase-mediated cell migration and has anticancer activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 82.00 | |
5 mg | In stock | $ 197.00 | |
10 mg | In stock | $ 372.00 | |
25 mg | In stock | $ 629.00 | |
50 mg | In stock | $ 896.00 | |
100 mg | In stock | $ 1,220.00 | |
500 mg | In stock | $ 2,450.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 226.00 |
Description | MLS000544460 is a highly selective and reversible Eya2 phosphatase inhibitor (Kd: 2.0 μM, IC50: 4 μM).MLS000544460 exhibits inhibitory effects on Eya2 phosphatase-mediated cell migration and has anticancer activity. |
Targets&IC50 | Eya2 phosphatase:(kd)2.0 μM , Eya2 phosphatase:4 μM , Eya2 phosphatase:2.0 μM(kd), Eya2 phosphatase:4 μM |
In vitro |
MLS000544460 binds to Eya2 ED (dialyzed into 10 μM EDTA to remove Mg2+) with a Kd of 0.80 μM.[1] MLS000544460 (10 μM) inhibits Eya2-mediated cell migration in human Eya2, Eya2 phosphatase-dead (D274N), and YFP (as a negative control) expressing MCF10A cells.[1] |
Molecular Weight | 341.36 |
Formula | C17H12FN3O2S |
CAS No. | 352336-36-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (87.88 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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MLS000544460 352336-36-8 Metabolism Phosphatase MLS-000544460 MLS 000544460 inhibitor inhibit