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Magnolioside

🥰Excellent
Catalog No. TN1905Cas No. 20186-29-2

Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.

Magnolioside

Magnolioside

🥰Excellent
Purity: 98.32%
Catalog No. TN1905Cas No. 20186-29-2
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.
Pack SizePriceAvailabilityQuantity
1 mg84 €In Stock
5 mg214 €In Stock
10 mg333 €In Stock
25 mg563 €In Stock
50 mg803 €In Stock
100 mg1.111 €In Stock
1 mL x 10 mM (in DMSO)233 €In Stock
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Purity:98.32%
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Product Introduction

Bioactivity
Description
Magnolioside has anti-plasmodial activity, shows notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum. It also shows a moderate antibacterial activity against Staphylococcus aureus CIP 53.154.Magnolioside exhibits significant neuroprotective activities against glutamate-induced toxicity.
In vitro
Using antiplasmodial activity-guided fractionation, five coumarins, marmesinin (1), nodakenin (2), skimmin (3), apiosylskimmin (4), and Magnolioside (5), were isolated and evaluated for in vitro antiplasmodial activity, as well as for their cytotoxic potential on SK-OV-3 cancer cell lines. Compounds 1 and 5 showed notable growth inhibitory activity against chloroquine-sensitive strains of P. falciparum with IC(50) values of 5.3 and 8.2 μM. The compounds showed no significant cytotoxicity (IC(50) > 100 μM) toward the SK-OV-3 cancer cell line[1]
Chemical Properties
Molecular Weight354.31
FormulaC16H18O9
Cas No.20186-29-2
SmilesCOc1cc2oc(=O)ccc2cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/ml (155.23 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8224 mL14.1119 mL28.2239 mL141.1194 mL
5 mM0.5645 mL2.8224 mL5.6448 mL28.2239 mL
10 mM0.2822 mL1.4112 mL2.8224 mL14.1119 mL
20 mM0.1411 mL0.7056 mL1.4112 mL7.0560 mL
50 mM0.0564 mL0.2822 mL0.5645 mL2.8224 mL
100 mM0.0282 mL0.1411 mL0.2822 mL1.4112 mL

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