Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 30.00 | |
100 mg | In stock | $ 42.00 | |
200 mg | In stock | $ 58.00 | |
500 mg | In stock | $ 89.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Mitotane (NCI-C04933) is a derivative of the insecticide DICHLORODIPHENYLDICHLOROETHANE that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression. |
Synonyms | Mitotan, o,p'-DDD, NCI-C04933, 2,4′-DDD |
Molecular Weight | 320.04 |
Formula | C14H10Cl4 |
CAS No. | 53-19-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 60 mg/mL (187.5 mM)
Ethanol: 60 mg/mL (187.5 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mitotane 53-19-0 Apoptosis Neuroscience AChR drug-drug interactions cholesterol inhibit Inhibitor antineoplastic Mitotan HepaRG o,p'-DDD corticotroph cells NCI-C04933 2,4′-DDD adrenocortical carcinoma TαT1 H295R NCI-C 04933 NCI-C-04933 inhibitor