Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 197.00 | |
5 mg | In stock | $ 456.00 | |
10 mg | In stock | $ 668.00 | |
25 mg | In stock | $ 1,060.00 | |
50 mg | In stock | $ 1,420.00 | |
100 mg | In stock | $ 1,920.00 | |
500 mg | In stock | $ 3,850.00 |
Description | OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. |
Targets&IC50 | anandamide cellular uptake(ki):2.4 μM(Ki) |
In vitro | OMDM-1 is anovel potent and selective inhibitors of ACU?and one 'hybrid' agonist of CB(1) and VR1 receptors (OMDM-6).?Unlike other compounds of the same type, OMDM-1, OMDM-2, and OMDM-6 were very stable to enzymatic hydrolysis by rat brain homogenates.The (R)- and, particularly, the (S)-1'-(4-hydroxybenzyl) derivatives of N-oleoylethanolamine and AEA (OMDM-1, OMDM-2, OMDM-3, and OMDM-4) inhibited to a varied extent ACU in RBL-2H3 cells (K(i) ranging between 2.4 and 17.7 micro M), the oleoyl analogues (OMDM-1 and OMDM-2, K(i) 2.4 and 3.0 micro M, respectively) being 6- to 7-fold more potent than the arachidonoyl analogues (OMDM-3 and OMDM-4). [1]. |
Synonyms | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide |
Molecular Weight | 431.65 |
Formula | C27H45NO3 |
CAS No. | 616884-62-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 30mg/ml
dimethyl formamide: 30mg/ml
DMSO: 55 mg/mL (127.42 mM)
You can also refer to dose conversion for different animals. More
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OMDM-1 616884-62-9 Metabolism Endogenous Metabolite vanilloid cells CB1 receptor type RBL-2H3 uptake FAAH cannabinoid (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide VR1 inhibit Inhibitor CB2 OMDM1 acids fatty OMDM 1 inhibitor